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Development of a Generalizable Strategy for Converting Metabolite Binding Proteins into Metabolite Responsive Transcription Factors

Description:

Metabolite biosensors are powerful tools for basic biological research, medical diagnostics, and biotechnological applications. However, a generalizable strategy for developing new metabolite biosensors when an existing sensor cannot be found in nature, is a persistent challenge. Furthermore, while transcription factor biosensors have the broadest range of applications, the pool of...

Keyword:

Bioengineering, Transcription factor, Synthetic biology, Promoter engineering, Protein engineering, and Metabolic engineering

Subject:

Interdepartmental Biological Sciences (IBiS) Graduate Program

Creator:

Andrew Younger

Owner:

Scholarly Digital Publishing

Date Uploaded:

04/18/2018

Date Modified:

04/18/2018

Date Created:

2017-01-01

Resource Type:

Dissertation
Engineering Cell-free Metabolism for Pathway Prototyping and Biomanufacturing

Description:

Pollution-intensive industrial manufacturing processes threaten the health of ecosystems and societies through toxic waste streams and energy intensive processes that lead to greenhouse gas emissions. Biological systems present more sustainable routes to many useful industrial chemicals by using enzymes at low temperatures, but the time and effort required to optimized...

Keyword:

Cell-free, Synthetic biology, Metabolic engineering, and Biomanufacturing

Subject:

Molecular biology and Chemical engineering

Creator:

Rasor, Blake

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

08/23/2023

Date Created:

2023-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_994770 and http://dissertations.umi.com/northwestern:16630

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Development of a Generalizable Strategy for Converting Metabolite Binding Proteins into Metabolite Responsive Transcription Factors

Engineering Cell-free Metabolism for Pathway Prototyping and Biomanufacturing

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