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  1. Bioinformatics Analysis of Top-Down Mass Spectrometry Data

    Work
    Description: Traditional bottom-up mass spectrometry-based proteomics relies on the use of an enzyme, often trypsin, to generate small peptides (typically < 25 amino acids long). In top-down proteomics, proteins remain intact and are directly measured within the mass spectrometer. This technique, while inherently simpler than bottom-up proteomics, generates data which must...
    Keyword: ProSight Lite, Top-down, Bioinformatics, Intact protein, Mass spectrometry, and Proteomics
    Creator: Paul M Thomas, Luca Fornelli, Ryan T Fellers, Neil L Kelleher, and Caroline J DeHart
    Depositor: Joseph Brent Greer
    Owner: Proteomics Center Of Excellence
    Publisher: Springer
    Date Uploaded: 08/03/2017
    Date Modified: 08/07/2017
    Date Created: 2017-02-02
    Rights: Attribution-NonCommercial-NoDerivs 3.0 United States
    Resource Type: Dataset
    Identifier: doi:10.21985/N2Q07P