Index Catalog // Arch : Northwestern University Institutional Repository

Description:: Transcription is tightly regulated to ensure genes are appropriately expressed both temporally and spatially. This tight regulation governs various processes within the cell, such as differentiation and cell identity, cellular maintenance, and dynamic responses to external signals. Transcription factors (TFs) coordinate these various gene programs and in particular, are key...
Keyword:: Repressor, NAFLD, PPAR alpha, BCL6, Transcription, and Metabolism
Subject:: Molecular biology and Biology
Creator:: Sommars, Meredith Anne
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/12/2020
Date Created:: 2019-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_663025 and http://dissertations.umi.com/northwestern:14672

Description:: The blueprint of life is contained within the sequence of an organism’s genome. While virtually all cells of an individual multicellular eukaryotic organism contain a near identical code of nucleic acid sequences, an organism must give rise to and maintain a varied set of cells and phenotypes. As such, sequence...
Keyword:: Genome, Epidermal Differentiation, Nuclear Organization, and Transcription
Subject:: Molecular biology, Genetics, and Cellular biology
Creator:: Garza-Gongora, Arturo
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/12/2020
Date Created:: 2018-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_617313 and http://dissertations.umi.com/northwestern:14401

Description:: Transcription of nucleic acids (DNA and RNA) is a hallmark of life, taking the information stored within genomic nucleic acids and converting it into a form that is useful for producing the proteins necessary for cellular and organismal function. In eukaryotes, transcription of DNA into messenger RNA (mRNA) requires the...
Keyword:: Virology, Paramyxovirus, Cryo-EM, Mediator, Polymerase, and Transcription
Subject:: Molecular biology, Biochemistry, and Biophysics
Creator:: Abdella, Ryan
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 04/15/2021
Date Created:: 2021-01-01
Resource Type:: Dissertation
Alternate Identifier:: http://dissertations.umi.com/northwestern:15490 and etdadmin_upload_797897

Description:: Chromatin organization involves a hierarchy of length scales ranging from a few tens of nanometers in nucleosomes to hundreds of nanometers for chromosomal territories. This physical nanostructure is regulated by the genetic code, differential methylation and histone modifications that comprise the histone code, as well as non-molecular factors, such as...
Keyword:: Physicochemical, Nanoscale, Chromatin, and Transcription
Subject:: Interdepartmental Biological Sciences (IBiS) Graduate Program
Creator:: Greta Mary Wodarcyk
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/14/2019
Date Modified:: 10/14/2019
Resource Type:: Dissertation

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