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Filtering by: Keyword basal ganglia Resource type Dissertation Subject Neurosciences

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Description:: Approximately 80-90% of individuals with Parkinson’s disease (PD) develop motor speech impairments, predominantly in the form of voice dysfunction. It is known that the motor symptoms of PD arise from degeneration of the dopamine producing neurons in the substantia nigra and dysregulation of basal ganglia motor pathways. It is also...
Keyword:: neuroimaging, dysarthria, fMRI, basal ganglia, hypophonia, and Parkinson's disease
Subject:: Neurosciences and Communication
Creator:: Manes, Jordan Leigh
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/01/2021
Date Created:: 2020-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_759611 and http://dissertations.umi.com/northwestern:15211

Description:: The basal ganglia are a remarkably complicated and interconnected tangle of subcortical nuclei whose exact function and composition are hotly debated to this day. What is plainly obvious, however, is that loss of dopaminergic modulation in the basal ganglia, as is the case in Parkinson’s disease (PD) following the progressive...
Keyword:: in vivo electrophysiology, anesthesia, basal ganglia, optogenetics, and 6-hydroxydopamine
Subject:: Neurosciences
Creator:: Kovaleski, Ryan Francis
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 01/21/2021
Date Created:: 2020-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_720363 and http://dissertations.umi.com/northwestern:15020

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