Minimal mathematical models are used to understand complex phenomena in the physical, biological, and social sciences. This modeling philosophy never claims, nor even attempts, to fully capture the mechanisms underlying the phenomena, and instead offers insights and predictions not otherwise possible. Here, we build and explore minimal dynamical systems models...
Chronic pain is a prevalent and under-treated condition that remains a mystery to the medical system and a major social and economic problem. Unfortunately, there is no single treatment superior to others for relieving chronic pain. While recent scientific discoveries have provided us with functional and anatomical brain biomarkers of...