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Plakophilin 2: Critical Roles in Intercellular Junction Assembly and Maturation via Regulation of Protein Kinase C and Actin

Description:

Desmosomes are adhesive complexes found at sites of intercellular contact that are essential for mediating cell-cell adhesion. These junctions undergo regulated assembly and reorganization during processes such as embryogenesis and wound healing. Plakophilins (PKPs) are armadillo family members related to the classic cadherin-associated protein p120ctn. PKPs localize to the cytoplasmic...

Keyword:

desmosome, cytoskeleton, cell-cell adhesion, armadillo, and plakophilin

Subject:

Integrated Graduate Program in the Life Sciences

Creator:

Amanda Elisabeth Bass-Zubek

Owner:

Scholarly Digital Publishing

Date Uploaded:

09/20/2018

Date Modified:

09/20/2018

Date Created:

2008-09-18

Resource Type:

Dissertation