Index Catalog // Arch : Northwestern University Institutional Repository

Description:: Dopaminergic neurons in the substantia nigra pars compacta are richly innervated by GABAergic neurons. The postsynaptic effects of GABA on SNc DA neurons are mediated by a mixture of GABAA and GABAB receptors. Although activation of GABAA receptors inhibits spike generation, the consequences of GABAB receptor activation are less well...
Keyword:: gabab, pka, substantia nigra, dopamine, and sk channel
Subject:: Interdepartmental Neuroscience Program (NUIN)
Creator:: Chad Michael Estep
Owner:: Scholarly Digital Publishing
Date Uploaded:: 03/22/2018
Date Modified:: 03/22/2018
Date Created:: 2016-01-01
Resource Type:: Dissertation

Description:: The floor plate (FP) is a ventral midline organizing structure of the developing neural tube that provides positional information using morphogen concentration gradients towards the production of diverse neuron types. In caudal regions the FP is non-neurogenic unlike the mesodiencephalic region of the FP that is highly neurogenic, and is...
Keyword:: boundary, Premammillary, Engrailed, Floor plate, Subthalamic, and dopamine
Subject:: Interdepartmental Neuroscience Program (NUIN)
Creator:: Navid Nouri
Owner:: Scholarly Digital Publishing
Date Uploaded:: 03/30/2018
Date Modified:: 03/30/2018
Date Created:: 2017-01-01
Resource Type:: Dissertation

Description:: The adhesive strategies of living creatures are diverse, ranging from temporary to permanent adhesions with various functions such as locomotion, self-defense, communication, colony formation, and so on. The classic example of temporary adhesion is the gecko, which is known for its ability to walk along vertical and even inverted surfaces;...
Keyword:: single-molecule, layer-by-layer, material-independent, Mussel, dopamine, and gecko
Subject:: Biomedical Engineering
Creator:: Haeshin Lee
Owner:: Scholarly Digital Publishing
Date Uploaded:: 09/11/2018
Date Modified:: 09/11/2018
Date Created:: 2008-03-27
Resource Type:: Dissertation

Description:: In vivo, substantia nigra pars compacta (SNc) dopaminergic neurons exhibit three spiking patterns – irregular, regular, and bursting. These distinct modes of activity are thought to underlie the different roles that dopamine (DA) plays in target structures within the basal ganglia. In particular, burst spiking in SNc DA neurons is...
Keyword:: burst firing, pedunculopontine nucleus, substantia nigra pars compacta, dopamine, and glutamate
Subject:: Interdepartmental Neuroscience Program (NUIN)
Creator:: Daniel James Galtieri
Owner:: Scholarly Digital Publishing
Date Uploaded:: 01/16/2019
Date Modified:: 01/16/2019
Date Created:: 2017-01-01
Resource Type:: Dissertation

Description:: Parkinson’s disease (PD) is the second most common neurodegenerative disorder, causing devastating disabilities in both motor and non-motor domains following the degeneration of dopamine (DA) producing neurons of the substantia nigra pars compacta (SNc). Current treatments are highly limited in efficacy, and no established treatments currently exist to alter disease...
Keyword:: molecular subtypes, dopamine, and Parkinson's disease
Subject:: Neurosciences
Creator:: Gaertner, Zachary Aaron
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 05/31/2023
Date Created:: 2023-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_983728 and http://dissertations.umi.com/northwestern:16518

Description:: Chronic stress is a significant risk factor for the development of numerous psychiatric disorders, including major depressive disorder (MDD). Individuals with MDD exhibit impairments in reward processing and decreased motivation to engage in previously-rewarding activities. Importantly, there is a large sex disparity in MDD diagnosis, such that it affects nearly...
Keyword:: corticosterone, motivation, and dopamine
Subject:: Neurosciences
Creator:: Holloway, Ashley
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 08/23/2023
Date Created:: 2023-01-01
Resource Type:: Dissertation
Alternate Identifier:: http://dissertations.umi.com/northwestern:16726 and etdadmin_upload_1012569

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