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A Platform for actively loading cargo RNA to elucidate limiting steps in EV-mediated delivery

Description:

Extracellular vesicles (EVs) mediate intercellular communication through transfer of RNA and protein between cells. Thus, understanding how cargo molecules are loaded and delivered by EVs is of central importance for elucidating the biological roles of EVs and developing EV-based therapeutics. While some motifs modulating the loading of biomolecular cargo into...

Keyword:

exosomes, VSVG, Lamp2b, active loading, MS2, extracellular vesicles, and microvesicles

Creator:

Michelle E. Hung and Joshua N. Leonard

Owner:

Chris Diaz

Publisher:

Co-action Publishing

Date Uploaded:

05/08/2017

Date Modified:

05/08/2017

Date Created:

2016-05-13

Resource Type:

Article