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Engineering the <em>in vitro</em> ovarian follicle microenvironment: Developmental regulation by the culture matrix and translational approaches for human fertility preservation

Description:

Improving cancer treatments are saving the lives of many young women, however these treatments often lead to premature infertility. The in vitro development of ovarian follicles would provide reproductive options to these women by supporting immature follicle growth following ovarian tissue cryobanking. In addition, the system provides a platform to...

Keyword:

follicle, fertility, alginate, ovary, tissue engineering, and in vitro follicle culture

Subject:

Chemical and Biological Engineering

Creator:

Erin Rochelle West

Owner:

Scholarly Digital Publishing

Date Uploaded:

09/19/2018

Date Modified:

09/19/2018

Date Created:

2008-06-19

Resource Type:

Dissertation
Engineering complex, heterogeneous ovarian microenvironments

Description:

Current biomaterials-based methods for in vitro ovarian follicle culture enable individual follicles or follicle classes to survive and carry out basic functions of the ovary, including hormone and release of mature oocytes upon gonadotropin stimulation. However, these current strategies do not support the survival and maturation of isolated primordial and...

Keyword:

3D bioprinting, follicle, ovary, tissue engineering, extracellular matrix, and ultrasound

Subject:

Biology

Creator:

Gargus, Emma S

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/01/2021

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:15147 and etdadmin_upload_744725

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Engineering the <em>in vitro</em> ovarian follicle microenvironment: Developmental regulation by the culture matrix and translational approaches for human fertility preservation

Engineering complex, heterogeneous ovarian microenvironments

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