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Filtering by: Keyword gene expression Resource type Dissertation Subject Developmental biology

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Stochastic Noise in Gene Expression Impacts Developmental Self-organization

Description:

Cells are often precisely organized into patterns within developing tissues. This precision must emerge from biochemical processes within, and between cells, that are inherently stochastic. I investigated the impact of stochastic gene expression on self-organized pattern formation, focusing on Senseless (Sens), a key target of Wnt and Notch signaling during...

Keyword:

gene expression, microRNA, cell fate, Drosophila, self-organization, and noise

Subject:

Applied mathematics, Statistics, and Developmental biology

Creator:

Giri, Ritika

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/01/2021

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_763812 and http://dissertations.umi.com/northwestern:15251
Analysis of Developmental Gene Regulation via Quantitative Imaging

Description:

Proper spatiotemporal expression of genes is essential during development. One method of regulation of signaling-responsive genes is at the level of transcription. In this work, I present the adaptation of single molecule fluorescent in situ hybridization for use in Drosophila imaginal disc tissues in order to more precisely quantify transcript...

Keyword:

gene expression, transcription, microscopy, bursting, in situ hybridization, and drosophila

Subject:

Systematic biology, Biology, and Developmental biology

Creator:

Bakker, Rachael

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/01/2021

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:15416 and etdadmin_upload_780973

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Stochastic Noise in Gene Expression Impacts Developmental Self-organization

Analysis of Developmental Gene Regulation via Quantitative Imaging

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