Index Catalog // Arch : Northwestern University Institutional Repository

Description:: Herpes stromal keratitis (HSK) is a potentially blinding inflammatory condition initiated by corneal infection with herpes simplex virus (HSV). As its name suggests, the host receptor herpes virus entry mediator (HVEM) facilitates HSV entry through interactions with a viral envelope glycoprotein. HVEM also bridges several signaling networks, binding ligands from...
Keyword:: herpes stromal keratitis, herpes simplex virus, immunopathology, inflammation, and cornea
Subject:: Life Sciences
Creator:: Rebecca Giovanna Edwards
Owner:: Scholarly Digital Publishing
Date Uploaded:: 02/21/2018
Date Modified:: 02/21/2018
Date Created:: 2016-01-01
Resource Type:: Dissertation

Description:: Some of the oldest drugs targeting metabolism are the antifolates such as aminopterin and methotrexate (MTX). MTX started being used in the 1950s to treat rheumatoid arthritis. Aminopterin and MTX both target one carbon metabolism and inhibit proliferation of cells. MTX was a potent inhibitor of inflammation, because it prevented...
Keyword:: macrophage, LPS, glutathione, metabolism, inflammation, and serine
Subject:: Biology
Creator:: Rodriguez, Arianne
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/12/2020
Date Created:: 2019-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_638528 and http://dissertations.umi.com/northwestern:14513

Description:: Macrophages are one of the most versatile immune cells in the immune system. They are found in nearly every tissue and organ throughout the body. Macrophages play important roles of orchestrating initiation and resolution of inflammation, such as sentineling against pathogens or engulfing apoptotic cells. Macrophages are able to respond...
Keyword:: macrophage, cardiovascular diseases, inflammation, and metabolism
Subject:: Immunology
Creator:: Zhang, Shuang
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/12/2020
Date Created:: 2018-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_623187 and http://dissertations.umi.com/northwestern:14427

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