Northwestern University

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Barbed End Regulation and the Formation of Actin Protrusive Structures

Description:

Barbed end regulation is critical to the formation of the actin-based protrusive structures, lamellipodia and filopodia. In this body of work we have chosen to focus on two main activities, filament termination by the heterodimeric Capping protein (CP) and continued filament elongation by the Ena/VASP family of proteins. We demonstrate...

Keyword:

actin protrusive structures, lamellipodia, filopodia, Ena/VASP, Capping Protein, and actin

Subject:

Integrated Graduate Program in the Life Sciences

Creator:

Derek Anthony Applewhite

Owner:

Scholarly Digital Publishing

Date Uploaded:

08/02/2018

Date Modified:

08/02/2018

Date Created:

2007-09-04

Resource Type:

Dissertation