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Structural Studies of Particulate Methane Monooxygenase in a Native Lipid Bilayer

Description:

Methanotrophs, bacteria that can metabolize methane, remain a promising solution to mitigating the effects of climate change by removing atmospheric methane and converting it to useful chemical precursors. However, a full understanding of the main enzyme they use to oxidize methane, particulate methane monooxygenase (pMMO), is critical for harnessing their...

Keyword:

cryogenic electron tomography, particulate methane monooxygenase, membrane protein, cryogenic electron microscopy, and cell-free protein synthesis

Subject:

Molecular biology, Biochemistry, and Biophysics

Creator:

Koo, Christopher Wellington

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

06/22/2022

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_897671 and http://dissertations.umi.com/northwestern:16003
Investigating How Membrane Mechanical Properties Affect the Expression, Folding, and Function of a Model Mechanosensitive Channel Protein

Description:

Mechanosensation is an essential behavior for cellular health that depends on the interactions between the plasma membrane and stretch-activated ion channels. To date, a few studies have measured the effect of membrane composition on protein behaviors from folding to function. However, the relationship between membrane mechanical properties and these behaviors...

Keyword:

electrophysiology, mechanobiology, membrane, protein folding, membrane protein, and polymer

Subject:

Biophysics

Creator:

Jacobs, Miranda

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

06/22/2022

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_893855 and http://dissertations.umi.com/northwestern:15990

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Structural Studies of Particulate Methane Monooxygenase in a Native Lipid Bilayer

Investigating How Membrane Mechanical Properties Affect the Expression, Folding, and Function of a Model Mechanosensitive Channel Protein

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