Index Catalog // Arch : Northwestern University Institutional Repository

Description:: Methanotrophs, bacteria that can metabolize methane, remain a promising solution to mitigating the effects of climate change by removing atmospheric methane and converting it to useful chemical precursors. However, a full understanding of the main enzyme they use to oxidize methane, particulate methane monooxygenase (pMMO), is critical for harnessing their...
Keyword:: cryogenic electron tomography, particulate methane monooxygenase, membrane protein, cryogenic electron microscopy, and cell-free protein synthesis
Subject:: Molecular biology, Biochemistry, and Biophysics
Creator:: Koo, Christopher Wellington
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 06/22/2022
Date Created:: 2022-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_897671 and http://dissertations.umi.com/northwestern:16003

Description:: Mechanosensation is an essential behavior for cellular health that depends on the interactions between the plasma membrane and stretch-activated ion channels. To date, a few studies have measured the effect of membrane composition on protein behaviors from folding to function. However, the relationship between membrane mechanical properties and these behaviors...
Keyword:: electrophysiology, mechanobiology, membrane, protein folding, membrane protein, and polymer
Subject:: Biophysics
Creator:: Jacobs, Miranda
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 06/22/2022
Date Created:: 2022-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_893855 and http://dissertations.umi.com/northwestern:15990

Description:: Harnessing the metabolic potential of methanotrophic bacteria is a compelling strategy for the bioremediation of environmentally harmful methane gas. Methanotrophs can activate a 105 kcal/mol C-H bond in methane at ambient conditions using metalloenzymes called methane monooxygenases (MMOs). Particulate methane monooxygenase (pMMO) is a copper-dependent, membrane-bound enzyme that is the...
Keyword:: copper, methane, methanotroph, metalloenzyme, particulate methane monooxygenase, and membrane protein
Subject:: Microbiology, Chemistry, and Biochemistry
Creator:: Ro, Soo Yeon
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/12/2020
Date Created:: 2019-01-01
Resource Type:: Dissertation
Alternate Identifier:: http://dissertations.umi.com/northwestern:14705 and etdadmin_upload_667719

Description:: Particulate methane monooxygenase (pMMO) is a membrane-bound metalloenzyme that oxidizes methane to methanol in methanotrophic bacteria. The nature of the pMMO active site and the overall metal content are controversial, with spectroscopic and crystallographic data suggesting the presence of a mononuclear copper center, a dinuclear copper center, a trinuclear center,...
Keyword:: methanotroph, particulate methane monooxygenase, membrane protein, and methanobactin
Subject:: Chemistry
Creator:: Amanda S. Hakemian
Owner:: Scholarly Digital Publishing
Date Uploaded:: 09/10/2018
Date Modified:: 09/10/2018
Date Created:: 2008-05-09
Resource Type:: Dissertation

LIBRARIES | ARCH