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Assembly of Ordered Microsphere Arrays: Platforms for Microarrays

Description:

Microarrays are powerful tools in gene expression assessment, protein profiling, and protein function screening, as well as cell and tissue analysis. With thousands of small array spots assembled in an ordered array, these small devices makes it possible to screen for multiple targets in a fast, parallel, high-throughput manner. The...

Keyword:

microarray, assembly, and microsphere

Subject:

Physics and Astronomy

Creator:

Wanling Xu

Owner:

Scholarly Digital Publishing

Date Uploaded:

09/19/2018

Date Modified:

09/19/2018

Date Created:

2008-06-25

Resource Type:

Dissertation
Genome-Scale Transcriptional Analysis of Megakaryocytic Cell Cultures Reveals Insights into Lineage-Specific Differentiation

Description:

Little is known about the transcriptional events underlying megakaryocytic (Mk) differentiation from hematopoietic stem cells. We sought to identify genes and pathways not previously associated with megakaryopoiesis and to evaluate the CHRF-288-11 (CHRF) megakaryoblastic cell line as a model system for investigating megakaryopoiesis. Using DNA microarrays, Q-RT-PCR, and protein-level assays,...

Keyword:

p53, microarray, differentiation, apoptosis, polyploidization, and megakaryocyte

Subject:

Chemical and Biological Engineering

Creator:

Peter Gebhard Fuhrken

Owner:

Scholarly Digital Publishing

Date Uploaded:

08/06/2018

Date Modified:

08/06/2018

Date Created:

2007-07-12

Resource Type:

Dissertation

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Assembly of Ordered Microsphere Arrays: Platforms for Microarrays

Genome-Scale Transcriptional Analysis of Megakaryocytic Cell Cultures Reveals Insights into Lineage-Specific Differentiation

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