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The Design and Application of Novel Biochemical Assays Based on the SAMDI-MS Platform

Description:

SAMDI-MS (Self-Assembled Monolayers for MALDI-TOF Mass Spectrometry) couples the use of chemically-defined self-assembled monolayers of alkane thiolates on gold surfaces with MALDI-TOF mass spectrometry for rapid characterization of the surfaces. Reactions performed on the surfaces can be quantified directly by detection of the reaction substrates and products. This rapid detection...

Keyword:

SAMDI, mass spectrometry, bioassay, chromodomains, cell-free reactions, and microfluidics

Subject:

Analytical chemistry, Materials Science, and Biochemistry

Creator:

O'Kane, Patrick Thomas

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:14615 and etdadmin_upload_661860
Electroosmotic Flow and Dispersion in Microfluidic Separation Systems

Description:

Motivated by applications to microfluidic separation systems like Capillary Electrophoresis (CE) and Capillary Electrochromatography (CEC), the research described in this dissertation analyzes through numerical and asymptotic methods the effect of variation in the wall zeta potential (or surface charge) on the electroosmotic flow field in a microchannel and the effect...

Keyword:

asymptotic, adsorption, microfluidics, separation, dispersion, and electrokinetic

Subject:

Mechanical Engineering

Creator:

Subhra Datta

Owner:

Scholarly Digital Publishing

Date Uploaded:

06/26/2018

Date Modified:

06/26/2018

Date Created:

2007-05-17

Resource Type:

Dissertation

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The Design and Application of Novel Biochemical Assays Based on the SAMDI-MS Platform

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