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Filtering by: Keyword sympathetic nervous system Resource type Dissertation Subject Integrated Graduate Program in the Life Sciences

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Description:: Early growth response genes (Egr1-4) are induced as immediate early genes by a variety of extracellular stimuli that influence cellular growth and differentiation. Egr transcriptional regulators modulate gene expression by binding to Egr response elements (ERE) in target genes. In this study, the low affinity p75 neurotrophin receptor (p75NTR) was...
Keyword:: Egr, sympathetic nervous system, dnEgr, neurotrophin signaling, and p75NTR
Subject:: Integrated Graduate Program in the Life Sciences
Creator:: Xiaoguang Guo
Owner:: Scholarly Digital Publishing
Date Uploaded:: 08/02/2018
Date Modified:: 08/02/2018
Date Created:: 2007-05-31
Resource Type:: Dissertation

Description:: Early Growth Response genes (Egr1-4) are transcriptional mediators of signals governing growth and differentiation. In sympathetic neuron-derived cell lines, Egr1 is induced by NGF signaling, which is required for sympathetic neuron survival, differentiation and target organ innervation. In the absence of identifiable sympathetic defects in Egr1-deficient mice, we investigated the...
Keyword:: NGF, sympathetic nervous system, and Egr3
Subject:: Integrated Graduate Program in the Life Sciences
Creator:: Laurie Christine Eldredge
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/01/2018
Date Modified:: 10/01/2018
Date Created:: 2008-12-08
Resource Type:: Dissertation

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