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  1. Establishing Novel Cell-free Platforms for the Synthesis of Protein-based Biologics

    Description: There is a need for alternative biomanufacturing solutions to produce novel medicines and help solve long-standing issues regarding difficult-to-treat diseases. Cell-free protein synthesis (CFPS) provides scientists with a new paradigm for producing proteins with an unprecedented freedom and control over the biomolecular machinery involved. In this document, I describe my...
    Keyword: synthetic biology, non-canonical amino acid, genome engineering, Cell-free protein synthesis, and antibodies
    Subject: Chemical and Biological Engineering
    Creator: Rey William Martin
    Owner: Scholarly Digital Publishing
    Date Uploaded: 10/21/2018
    Date Modified: 10/21/2018
    Date Created: 2017-01-01
    Rights: In Copyright
    Resource Type: Dissertation
  2. Computational design of Small Transcription Activating RNAs (STARs) for versatile and dynamic gene regulation

    Description: A longstanding goal of synthetic biology has been the programmable control of cellular functions. Central to this is the creation of versatile regulatory toolsets that allow for programmable control of gene expression. Of the many regulatory molecules available, RNA regulators offer the intriguing possibility of de novo design – allowing...
    Keyword: gene regulation, synthetic biology, RNA engineering, RNA, and transcription
    Subject: Synthetic Biology and RNA engineering
    Creator: James Chappell, Julius B. Lucks, Alexandra Westbrook, and Matthew Verosloff
    Owner: Julius Beau Lucks
    Publisher: MacMillan Publishers
    Language: English
    Date Uploaded: 08/03/2017
    Date Modified: 08/16/2017
    Date Created: 2017-08-03
    Rights: Attribution 3.0 United States
    Resource Type: Dataset
    Identifier: doi:10.21985/N28S9B