Northwestern University

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Structural and functional characterization and inhibition of Epstein-Barr virus fusion proteins gH, gL, and gp42

Description:

Epstein-Barr virus (EBV) is the cause of infectious mononucleosis and is associated with the etiology of several human cancers of lymphoid and epithelial cell origin, including Burkitt's lymphoma and nasopharyngeal carcinoma. It is an extremely prevalent virus in human populations worldwide. All herpesviruses, including EBV, infect cells by fusing the...

Keyword:

membrane fusion, peptide inhibitior, antiviral, viral entry, Epstein-Barr virus, and glycoprotein structure

Subject:

Interdepartmental Biological Sciences Program

Creator:

Austin Kirschner

Owner:

Scholarly Digital Publishing

Date Uploaded:

08/27/2018

Date Modified:

08/27/2018

Date Created:

2007-08-15

Resource Type:

Dissertation