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-
- Description:
- As machines take over the work of producing, organizing, and curating culture, it becomes increasingly important to examine the influence of algorithms in public memory work, through which the past is selectively and subjectively reconstructed to make meaning in the present. Accordingly, this dissertation intervenes at the intersection of public...
- Keyword:
- public memory, media archaeology, rhetoric, memorials, media studies, and algorithmic culture
- Subject:
- Rhetoric
- Creator:
- Lingo, Sarah Katherine
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_947105 and http://dissertations.umi.com/northwestern:16370
-
- Description:
- A fundamental materials science question is “why and how will this material form?” The experimental,computation, and time resources necessary to answer this question consume significant resources due to the predominantly trial-and-error based approaches common in materials research. This dissertation reintroduces a number of fundamental thermodynamics-based tools for the study of...
- Keyword:
- Density Functional Theory, Aqueous Synthesis, Driving Force, Thermodynamics, Pourbaix Diagram, and Speciation
- Subject:
- Physics, Chemistry, and Materials Science
- Creator:
- Walters, Lauren Nichole
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16360 and etdadmin_upload_946544
-
- Description:
- Understanding organization of soft materials on mesoscopic and nanoscopic scales is importantfor materials design. In this regard, non-van der Waals interactions such as hydrogen bonding and electrostatic interactions offer great opportunities due to the richness and diversity in morphological structures they produce. The primary reason for this is that these...
- Subject:
- Molecular physics and Materials Science
- Creator:
- Prusty, Debadutta
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16315 and etdadmin_upload_938426
-
- Description:
- Fausto Romitelli (1963-2004), one of the most inventive composers of his generation, created a musical language that draws inspiration from a multifaceted array of sources, including the technological landscape of daily life, the visual arts, poetry, literature, and philosophy. Furthermore, from early in his career, Romitelli incorporated elements in his...
- Keyword:
- Analysis, Music, and Romitelli
- Subject:
- Music theory and Musical composition
- Creator:
- Arrellin, Mathew
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16376 and etdadmin_upload_947312
-
- Description:
- Desmosomal cadherins are a recent evolutionary innovation that make up the adhesive core of highly specialized intercellular junctions called desmosomes. Desmosomal cadherins, desmogleins and desmocollins, are related to the classical cadherins but their cytoplasmic domains are tailored for anchoring intermediate filaments instead of actin to sites of cell-cell adhesion. The...
- Keyword:
- Keratinocyte, Desmosome, Retromer chaperone, Dsg1, SAM syndrome, and Endosomal trafficking
- Subject:
- Cellular biology
- Creator:
- Hegazy, Marihan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_944940 and http://dissertations.umi.com/northwestern:16344
-
- Description:
- Many computing technologies are primarily useful because of the existence of some set of data created by people, intentionally in some cases and unintentionally in others. For instance, technologies like search engines, recommender systems, classifiers, and language models are all dependent on digital records of things people have said, done,...
- Keyword:
- responsible artificial intelligence, data leverage, human-centered machine learning, data labor, and user-generated content
- Subject:
- Computer science and Communication
- Creator:
- Vincent, Nicholas
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_945620 and http://dissertations.umi.com/northwestern:16351
-
- Description:
- “Pornographic Bodies: Constructing Corporeality in Adult Film” explores how the body is theorized within pornography through issues of materiality, spacing, form, libidinal organization, and subject/object relations. This dissertation challenges the way existing porn studies scholarship has taken body to be a self-evident vessel containing the psychosexual dynamics of the performers...
- Keyword:
- Media, Corporeality, Film, Pornography, and Body
- Subject:
- Film studies
- Creator:
- Scott, Karly-Lynne
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_944948 and http://dissertations.umi.com/northwestern:16345
-
- Description:
- To better prepare for earthquakes, we need to know how large they will be, how strong the shaking will be, and how often they will occur. To answer these questions, seismologists look to past earthquakes to better understand future hazards. Earthquakes, however, are complex physical phenomena that occur on timescales...
- Keyword:
- Earthquake statistics, Seismology, and Probability models
- Subject:
- Geophysics
- Creator:
- Neely, James Scott
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_933449 and http://dissertations.umi.com/northwestern:16291
-
- Description:
- Since the mid-20th century, urbanization has altered the physical landscape and brought social, economic and lifestyle changes to populations worldwide. In the Global South, this has dramatically affected environmental conditions of settlements, communities, and households, with both positive and negative consequences for population health. The objective of this dissertation is...
- Subject:
- Physical anthropology
- Creator:
- McCabe, Kimberly A.
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_934882 and http://dissertations.umi.com/northwestern:16297
-
- Description:
- DNA is extremely versatile and powerful, both as a construct in biological applications and as a ligand in materials design due to the fact that its recognition properties can be programmed through sequence and length. Spherical nucleic acids (SNAs), nanoparticles surrounded by a dense shell of DNA or RNA, are...
- Keyword:
- Vaccines, DNA, Materials, DNA dendrons, Therapeutics, and Nanoparticle assembly
- Subject:
- Nanoscience and Chemistry
- Creator:
- Distler, Max E
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_935338 and http://dissertations.umi.com/northwestern:16301
-
- Description:
- Since its introduction as an artist’s pigment in the earth 20th century, titanium white has become one of the most common white pigments. The early formulations of titanium white contained anatase, which has been studied to facilitate degradation of oil paint under UV illumination. Around the 1940s production shifted to...
- Subject:
- Materials Science and Computational chemistry
- Creator:
- Schmitt, Thomas
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_941215 and http://dissertations.umi.com/northwestern:16325
-
- Description:
- Computational material engineering (CME) has increased the pace of material development many folds in recent years by taking advantage of computational tools such as using simulations as replacement to experiments, and building complicated processing-structure-property relationships using advanced machine learning tools. The importance of CME is underscored by new computation-based design...
- Subject:
- Design
- Creator:
- Ghumman, Umar Farooq
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_939364 and http://dissertations.umi.com/northwestern:16322
-
- Description:
- We consider constant scalar curvature K ̈ahler metrics on a smooth minimal model of general type in a neighborhood of the canonical class, which is the perturbation of the canonical class by a fixed K ̈ahler metric. We show that sequences of such metrics converge smoothly on compact subsets away...
- Subject:
- Mathematics
- Creator:
- Liu, Wanxing
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16350 and etdadmin_upload_945453
-
- Description:
- In this thesis, I explore the formation and evolution of neutron stars and millisecondpulsar populations in globular clusters using N-body simulations. In particular, I examine how the number of millisecond pulsars and the pulsar properties, including binary properties and different pulsar types, depend on the dynamical cluster environment. I demonstrate...
- Keyword:
- STAR CLUSTERS, N-BODY SIMULATIONS, PULSARS, NEUTRON STARS, and COMPACT OBJECTS
- Subject:
- Astronomy and Astrophysics
- Creator:
- Ye, Claire Shi
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_932107 and http://dissertations.umi.com/northwestern:16285
-
- Description:
- Wireless power strategies are critical to system level implementation of bio-integrated devices. To achieve mechanically robust, manufacturable systems, batteries are often integrated as an on-board power source to support sensing, wireless communication and signal conditioning. Unfortunately, most sources of battery power use hazardous and environmentally harmful materials, which frustrate incorporation...
- Subject:
- Chemistry, Materials Science, and Biomedical engineering
- Creator:
- Huang, Ivy
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_934213 and http://dissertations.umi.com/northwestern:16294
-
- Description:
- Cancer remains a leading cause of death worldwide, necessitating continued study to explore and unravel its complex etiology. For example, there has been a shift of focus in cancer treatment from surgery and radiotherapy to targeted chemo- and immunotherapies as we gain more knowledge on the hallmarks of cancer (e.g.,...
- Keyword:
- tumor microenvironment, nanomedicine, Checkpoint inhibitor, spherical nucleic acids, gene expression/knockdown, and immunotherapy
- Subject:
- Nanotechnology, Oncology, and Immunology
- Creator:
- Chou, Liyushang
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_884998 and http://dissertations.umi.com/northwestern:15965
-
- Description:
- Tumor-initiating cells with reprogramming plasticity are thought to be essential for cancer development and metastatic regeneration in many cancers; however, the molecular mechanisms are not fully understood. We have previously identified that CD44, a breast tumor-initiating cell marker, drives mammosphere self-renewal and multicellular aggregation of circulating tumor cell (CTC) clusters,...
- Keyword:
- exosomes, CD44, cancer stem cells, extracellular vesicles, CD81, and breast cancer
- Subject:
- Molecular biology, Biology, and Cellular biology
- Creator:
- Ramos, Erika Kathryn
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16152 and etdadmin_upload_916551
-
- Description:
- Gerotranscendence involves feelings of coherence with one’s sense of self, greater acceptance of one’s own life, and connectedness to others across time and space. Gerotranscendence is thought to increase with age. The present study is the first longitudinal effort to investigate changes in gerotranscendence across late midlife using life story...
- Keyword:
- self-transcendence, gerontology, narrative identity, ego integrity, midlife, and life stories
- Subject:
- Developmental psychology, Personality psychology, and Clinical psychology
- Creator:
- Reischer, Hollen N.
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16318 and etdadmin_upload_938638
-
- Description:
- Given the enormous diversity that exists in our society today, the need intensifies for educators to create a transformative environment that fosters productive encounters with the differences that emerge in a diverse society. Nonetheless, limited attention has been devoted to generating a systematic understanding of how students engage with and...
- Subject:
- Education
- Creator:
- Chang, Amy A
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_947336 and http://dissertations.umi.com/northwestern:16378
-
- Description:
- The excitation of seismic waves depends on the geologic processes of an earthquake. The waveforms at seismic stations can be modeled as linear combinations of derivatives of Green's functions, which describe the response at the receiver location due to excitation at the seismic source location considering wave propagation effects given...
- Keyword:
- Moment Tensors, Moment Tensor Inversion, Seismic Source Processes, Non-Double-Couple Components, Big Data Analysis, and Moment Tensor Catalogs
- Subject:
- Geophysics
- Creator:
- Rösler, Boris
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_938604 and http://dissertations.umi.com/northwestern:16317
-
- Description:
- Dopamine neurons are characterized by their response to unexpected rewards, but some also fire during movement and in response to aversive stimuli. Dopamine neuron diversity has also been observed based on their genetic expression profiles, suggesting that different functions might map onto such genetic subtypes. However, this has not been...
- Keyword:
- Subtypes, Striatum, Dopamine, and SNc
- Subject:
- Neurosciences
- Creator:
- Azcorra, Maite
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16371 and etdadmin_upload_947134
-
- Description:
- Biomineralization relies on the regulation of localized environments to control how minerals are formed. Through the use of confinement and specific additives, the organism is able to change the energy landscape of nucleation and growth to build single crystals with unusual morphologies. In order to better understand the environments in...
- Subject:
- Materials Science
- Creator:
- Duggins, Danielle
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_937458 and http://dissertations.umi.com/northwestern:16309
-
- Description:
- From the 1990s through the 2000s, gross-out comedy – in the broadest terms, the style of physical comedy that emphasizes bodily functions and fluids, transgressive imagery and behavior, and shock value and disgust – triumphed as a subgenre of popular narrative film and television comedy. Gross-out comedy first emerged as...
- Keyword:
- disgust, irony, film comedy, and TV comedy
- Subject:
- Film studies
- Creator:
- Aspray, Benjamin Kole
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_944524 and http://dissertations.umi.com/northwestern:16341
-
- Description:
- External manipulation of soft matter underlies a multitude of advancements in far-from-equilibrium materials. The application of magnetic fields has proven tremendouslybeneficial due to its ability to impart rapid and precise changes throughout soft magnetic systems. This has led to scientists and engineers to develop composite materials that take advantage of...
- Keyword:
- dynamic magnetic fields, simulations, soft matter, membranes, theory, and superparamagnetism
- Subject:
- Computational physics
- Creator:
- Brisbois, Chase
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16357 and etdadmin_upload_946183
-
- Description:
- Drinking water treatment residuals (DWTRs) are waste materials generated during the clarification process of drinking water treatment. The application of DWTRs as sorbent materials offers an opportunity to reuse and add value to these materials. For instance, as metal sorbents, DWTRs could be used as active capping materials to remediate...
- Subject:
- Environmental science, Environmental engineering, and Sustainability
- Creator:
- Wallace, Samuel McDonald
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_934733 and http://dissertations.umi.com/northwestern:16295
-
- Description:
- Micro-X is a high-resolution X-ray spectroscopy sounding rocket mission that had its first flight in July 2018, becoming the first program to carry Transition-Edge Sensors (TES) and multiplexing Superconducting QUantum Interference Device (SQUID) readout electronics into space, successfully collect data, and subsequently recover the instruments. While a rocket pointing failure...
- Keyword:
- TES, Sounding Rocket, Microcalorimeter, SQUID multiplexing, and X-ray
- Subject:
- Astrophysics, Physics, and Low temperature physics
- Creator:
- Manzagol-Harwood, Renee Elisabeth
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_937247 and http://dissertations.umi.com/northwestern:16308
-
- Description:
- Phonotactic patterns are generalizations that govern the order of consonants and vowels, within words and syllables. Certain second-order phonotactic patterns—those that relate multiple sounds within a syllable, such as “if the vowel is [ɪ], then [s] can only appear at the end of the syllable”—require a period of sleep-based consolidation...
- Keyword:
- speech production, phonotactics, adult language learning, pattern learning, motor learning, and phonology
- Subject:
- Cognitive psychology, Language, and Linguistics
- Creator:
- Mirea, Nicole Irene
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16373 and etdadmin_upload_947262
-
- Description:
- G protein-coupled receptors (GPCRs) are the largest family of membrane receptors in humans and play a role in nearly all physiological processes. Among GPCRs, metabotropic glutamate receptors (mGluRs) are a structurally distinct family of synaptic receptors that are essential in regulating neurotransmission and synaptic plasticity. Due to their important regulatory...
- Keyword:
- structural dynamics, mGluRs, conformational dynamics, membrane proteins, smFRET, and GPCRs
- Subject:
- Pharmacology, Biochemistry, and Biophysics
- Creator:
- Liauw, Brandon Wey-Hung
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_937523 and http://dissertations.umi.com/northwestern:16310
-
- Description:
- Cancer has long been the second-leading cause of death in the United States and represents the leading cause of death in midlife (age 40-60). While the prognosis for many cancers has vastly improved over the last thirty years, many cancers remain elusive due to the late-onset of symptoms, the specific...
- Keyword:
- Antibodies, Protein Switch, Cell Patterning, Machine Learning, and Breast Cancer
- Subject:
- Biomedical engineering
- Creator:
- Sykora, Daniel Joseph
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_936187 and http://dissertations.umi.com/northwestern:16305
-
- Description:
- This dissertation reinterprets Michel Foucault’s theory of sovereignty to offer an explanation and critique of repressive state violence. Commentators typically locate Foucault’s contribution to political thought in concepts of power that are irreducible to sovereignty or the state. In contrast, I draw on Foucault’s early genealogies of power to argue...
- Keyword:
- Violence, Foucault, Critique, Sovereignty, and Genealogy
- Subject:
- Philosophy
- Creator:
- Lichtenstein, Eli
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_934011 and http://dissertations.umi.com/northwestern:16293
-
- Description:
- The ability to regenerate lost tissues or organs is widespread in the animal kingdom, but the mechanistic basis underpinning this process is incompletely understood. The planarian flatworm Schmidtea mediterranea has an incredibly robust and flexible capacity for regeneration, able to regenerate an entire organism from arbitrary starting points. This makes...
- Subject:
- Molecular biology
- Creator:
- Gittin, David I
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16379 and etdadmin_upload_947402
-
- Description:
- The vibrational and rotational degrees of freedom in a molecule add complexity that complicate optical cycling and state preparation procedures. However, the same additional degrees of freedom also make molecules suitable candidates for tests of physics beyond the standard model. A precision measurement of the transition energy between two vibrational...
- Keyword:
- Photon Recoil Readout, Mixed-Species Ion Crystal, Spectroscopy, Sideband Cooling, SiO+, and Single Molecule
- Subject:
- Optics, Molecular physics, and Atomic physics
- Creator:
- Dragan, James
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_933373 and http://dissertations.umi.com/northwestern:16290
-
- Description:
- Making the Coast Pacific is an environmental history of violence against places, plants, and people. Mexico's Pacific Coast region was a key site for oilseed agriculture and industrialization, which resulted in environmental violence and injustice. Since the region with Mexico's largest population of afro-descendants, Costa Chica, was also Mexico's leading...
- Keyword:
- Agrarian reform, Agribusiness history, Oilseed crops, Environmental Violence, Afro-Mexico, and Agrochemicals
- Subject:
- Latin American history, Science history, and Environmental studies
- Creator:
- Porter, Jayson Maurice
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16288 and etdadmin_upload_933029
-
Recurrent inhibition within olfactory networks shapes noise correlations and stimulus discrimination
- Description:
- Each second, living organisms take in sensory input from an ever-changing environment and respond appropriately. Identifying and contextualizing stimuli is critical for survival, and it often necessitates distinguishing between sensory experiences that are similar to each other. Pattern separation characterizes the mechanisms by which neuronal networks extract and highlight differences...
- Keyword:
- Sensory processing, Neuroscience, and Olfaction
- Subject:
- Applied mathematics
- Creator:
- Wang, Angelia Feiyang
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_945895 and http://dissertations.umi.com/northwestern:16353
-
- Description:
- A massive amount of data is generated every second all around the world. Machine learning becomes the most attractive solution to consume the data fuel and transform it into productivity. It has yielded great results in many fields, such as healthcare, marketing, finance, etc. Machine learning models are usually designed...
- Subject:
- Computer science
- Creator:
- Xue, Ye
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16381 and etdadmin_upload_947914
-
- Description:
- Nucleic acid therapeutics can be drug molecules with high programmability, minimal off-target effects, and the capability to address “undruggable” targets for diseases. In addition, each time a new drug is needed, one needs to only change the sequence as opposed to finding an entirely new structure. One nucleic acid type...
- Keyword:
- RNAi, siRNA, gene therapy, structure-function, spherical nucleic acid, and nanoparticle
- Subject:
- Nanotechnology, Pharmaceutical sciences, and Biomedical engineering
- Creator:
- Vasher, Matthew Kuo
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_938909 and http://dissertations.umi.com/northwestern:16319
-
- Description:
- Understanding the photophysical processes of organic materials is important for utilizing them as functional photonic materials. Typical photophysical processes include intersystem crossing, charge transfer (CT), symmetry-breaking charge separation (SB-CS), singlet fission (SF), etc. There are serval factors that can lead to different photophysical processes, such as the molecular energy levels,...
- Subject:
- Physical chemistry and Chemistry
- Creator:
- Lin, Chenjian
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_947331 and http://dissertations.umi.com/northwestern:16377
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- Description:
- Industrial processes heavily rely on catalysts to control product selectivity and lower energy barriers required for chemical transformations. Catalysts are most commonly solid heterogeneous catalysts that facilitate separations from reaction mixtures and enhance recyclability. Heterogeneous catalysts used in industrial processes exhibit efficacious results, but in certain instances drawing structure-function relationships...
- Keyword:
- Polymerization, Oligomerization, Metal–Organic Frameworks, Structure-property relationships, and Heterogeneous catalysis
- Subject:
- Chemistry and Materials Science
- Creator:
- Goetjen, Timothy
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_938937 and http://dissertations.umi.com/northwestern:16320
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- Description:
- Genetic variation in genes regulating metabolism may be advantageous in some settings but not others. The non-failing adult heart relies heavily on fatty acids as a fuel substrate and source of ATP. In contrast, the failing heart favors glucose as a fuel source. A bootstrap analysis for genes with deviant...
- Keyword:
- Heart Failure, Glucose, Cardiomyopathy, Drosophila, Metabolism, and Mitochondria
- Subject:
- Molecular biology, Gender studies, and Cellular biology
- Creator:
- Fischer, Julie Anne
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16326 and etdadmin_upload_941216
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- Description:
- Early life adversity predicts greater health risk in later life across multiple outcomes, including cardiovascular disease (CVD) and all-cause mortality. While biological pathways are incompletely understood, evidence is increasingly highlighting immune function, specifically chronic inflammation, which is implicated in cardiometabolic diseases, certain cancers, and all-cause mortality. Links between early adversity...
- Subject:
- Physical anthropology
- Creator:
- Aronoff, Jacob
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_945998 and http://dissertations.umi.com/northwestern:16356
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- Description:
- One of the fundamental questions in developmental biology is how a single cell gives rise to a complex organism. More specifically, how a totipotent egg divides into cells that become increasingly restricted in their potential. Development is a process of increasingly restricted cellular potential, and here I home in on...
- Keyword:
- Xenopus, Pluripotency, Neural Default Model, BMP, Smads, and Activin
- Subject:
- Biology and Developmental biology
- Creator:
- Johnson, Kristin Lorette
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16347 and etdadmin_upload_945075
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- Description:
- In this dissertation, I conducted 2 studies that resulted in 3 manuscripts. This dissertation consists of 6 chapters that include the 3 manuscripts. The overarching research question is How does context affect the work of quality improvement (QI) practitioners? To answer this larger research question, which is central to the...
- Keyword:
- Context, Quality Improvement, Scoping Review of Reviews, and Qualitative Research
- Subject:
- Health sciences
- Creator:
- Terwilliger, Iva Alyse
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_945966 and http://dissertations.umi.com/northwestern:16355
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- Description:
- Much prior research on memory systems has focused on establishing dissociations between different types of memory based on behavior, subjective experience, and the brain: explicit memory depends on the medial temporal lobe and is thought to operate consciously through a relatively slower processing bottleneck, while implicit memory is a term...
- Subject:
- Psychology
- Creator:
- Schmidt, Kevin
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_890051 and http://dissertations.umi.com/northwestern:15980
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- Description:
- This thesis presents results on photophysics and spin dynamics of photoactive organic molecules that possess one unpaired electron spin in the ground state and two or three unpaired spins upon photoexcitation. The excited state dynamics of the systems were studied using transient optical absorption spectroscopies and non-Boltzmann population on the...
- Subject:
- Physical chemistry and Chemistry
- Creator:
- Mao, Haochuan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_946833 and http://dissertations.umi.com/northwestern:16364
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- Description:
- Dopamine (DA) neurons are involved in many brain functions, and their dysfunction is associated with several neurodegenerative diseases. In recent years, our lab and others have found that DA neurons are molecularly diverse through single-cell gene expression profiling. An outstanding question in the field is whether this heterogeneity is encoded...
- Subject:
- Developmental biology
- Creator:
- Pereira Luppi, Maria Milagros
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16348 and etdadmin_upload_945123
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- Description:
- Selecting the best material to deliver optimum performance in real-world applications is one of the most significant challenges in engineering. Hundreds of thousands of computationally-predicted, but experimentally unexplored materials exist today in the public inorganic material databases as candidates for consideration. This thesis discusses three projects in the domain of...
- Keyword:
- statistical modeling, materials design, uncertainty quantification, materials selection, computational materials, and materials informatics
- Subject:
- Materials Science
- Creator:
- Gopakumar, Abhijith Mini
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_947056 and http://dissertations.umi.com/northwestern:16368
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- Description:
- This research questions how institutional logics shape and change through the event sequencing of institutional reforms. Literature reviewed on sequences of social events underspecifies the enchainment of events, i.e., the set of social processes that both links events and also renders the sequence meaningful beyond summing its individual events. My...
- Keyword:
- institutional logics, institutional reforms, organizational institutionalism, Latin America, event sequencing, and qualitative methods
- Subject:
- Management and Organization theory
- Creator:
- Milner, Daniel
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_941589 and http://dissertations.umi.com/northwestern:16331
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- Description:
- Superconducting-circuit based platforms are strong contenders in the race to build a quantum computer.While the transmon has had extraordinary success as the leading superconducting qubit modality, there are reasons to believe that other types of qubits could possess relative benefits in terms of noise immunity, anharmonicity, or extensibility. In this...
- Keyword:
- fluxonium, Superconducting circuits, Quantum computing, and current mirror
- Subject:
- Physics and Quantum physics
- Creator:
- Weiss, Daniel Kamrath
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_933500 and http://dissertations.umi.com/northwestern:16292
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- Description:
- Fat represents an important source of energy for ovarian cancer (OC) cells and is supplied either through import from the tumor milieu or via de novo lipogenesis. During fast tumor growth, when nutrients are scarce, lipogenesis becomes the primary source of fatty acids. Stearoyl-CoA desaturase (SCD), a rate-limiting enzyme in...
- Keyword:
- ER stress, Fatty acids, Ovarian cancer, and Lipid metabolism
- Subject:
- Bioinformatics, Oncology, and Cellular biology
- Creator:
- Zhao, Guangyuan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_940639 and http://dissertations.umi.com/northwestern:16324
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- Description:
- From the early usage of metallic thin films as mirrors tracing back to 2900 BC, to the modern thin film photonic circuits as a mature optical processing platform, and to the growing class of atomically-thin two-dimensional (2D) materials with diverse and tailorable properties, thin film materials have played an important...
- Keyword:
- Two-dimensional materials, Photonic circuits, Thin film materials, Topological photonics, Electron-beam lithography, and Optical materials
- Subject:
- Physics and Materials Science
- Creator:
- Liu, Pufan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_946295 and http://dissertations.umi.com/northwestern:16358