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-
- Description:
- In December 1889, a few weeks after the monarchy in Brazil was replaced by a republican government, seventy-year-old USAmerican poet Walt Whitman wrote a poem called “A Christmas Greeting” to welcome the “Brazilian brother” into democracy. Though filled with hope and excitement for yet another republic born in the Americas,...
- Keyword:
- Poetry and Poetics, Lusophone Studies, Translation, Hemispheric/ Transnational Studies, Walt Whitman, and Brazil
- Subject:
- Comparative literature and Latin American studies
- Creator:
- Anzini, Patrícia
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_626611 and http://dissertations.umi.com/northwestern:14455
-
- Description:
- Proteins are a class of nanoscale building block with remarkable chemical complexity and sophistication: their diverse functions, shapes and symmetry, and atomically monodisperse structures far surpass the range of nanoparticles that can be accessed synthetically. The chemical topology of proteins that drive their assembly into higher order materials are central...
- Subject:
- Chemistry
- Creator:
- McMillan, Janet
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14624 and etdadmin_upload_662062
-
- Description:
- Innovations are adopted by individuals and spread to other individuals. They are adopted at different rates, some are never adopted at all, some are abandoned, and some become the new norms. A very extensive evidence-based research and practice paradigm that studies how innovations spread is called diffusion of innovations. This...
- Keyword:
- multipartite networks, complex networks, diffusion of innovations, and network reconstruction
- Subject:
- Statistics
- Creator:
- Lee, Hyojun Ada
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14765 and etdadmin_upload_678904
-
- Description:
- This thesis focuses on exploring the explanatory and discovery potential of the four-neutrino and enhanced neutrino magnetic and electric dipole moments hypotheses when applied to the NOvA/T2K discrepancy and the XENON1T anomaly, respectively. Firstly, we study the effect of a very light (sub eV) sterile neutrino on the NOvA/T2K anom-...
- Keyword:
- Particles, Neutrinos, Physics, Phenomenology, Neutrino Magnetic Moment, and Sterile Neutrino
- Subject:
- Physics and Particle physics
- Creator:
- Jusino Sánchez, Giancarlo
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_985471 and http://dissertations.umi.com/northwestern:16558
-
- Description:
- The purpose of this thesis is to derive three results in probability theory. The first is a proof that small powers of the normalized absolute characteristic polynomial of a random matrix sampled from either the Gaussian Orthogonal or Symplectic Ensemble converges in law to a Gaussian multiplicative chaos measure. The...
- Keyword:
- Probability and Random Matrices
- Subject:
- Mathematics
- Creator:
- Kivimae, Pax
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_923657 and http://dissertations.umi.com/northwestern:16191
-
- Description:
- During the 1870s and 1880s, state governments in the former slaveholding South established eleven public institutions for black higher learning. Given the volatile, impoverished, often repressive climate of the region, how did black political and educational leaders mobilize to expand state support for black higher education? Furthermore, how did they...
- Keyword:
- Reconstruction, Jim Crow, African American, Education, Higher education, and Southern states
- Subject:
- American history, Black history, and Education history
- Creator:
- Soares, Leigh Alexandra
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_662076 and http://dissertations.umi.com/northwestern:14626
-
- Description:
- Cardiac Magnetic Resonance (CMR) is a promising non-invasive imaging technique capable of assessing cardiovascular function and anatomy for both adult and pediatric patients without the need for ionization energy. Even with the stated benefits, CMR utilization in the clinic is low (~1-2%) due in large part to long acquisition time...
- Keyword:
- Cardiovascular MRI, compressed sensing, real-time, adult and pediatric, deep learning, and free-breathing
- Subject:
- Medical imaging
- Creator:
- Haji-valizadeh, Hassan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_682286 and http://dissertations.umi.com/northwestern:14782
-
- Description:
- Recent studies have shown that many high profile studies in biology could not be reproduced, calling into questions the legitimacy of their findings. These reports have the potential to greatly jeopardize the credibility of scientists in the field as well as erode public confidence in the scientific enterprise. Computational research...
- Keyword:
- Sequencing, Reproducibility, and Computational Biology
- Subject:
- Bioinformatics and Engineering
- Creator:
- Liu, Sophia Shou
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_658807 and http://dissertations.umi.com/northwestern:14578
-
Implications of Within-Species Root and Shoot Trait Variation and Plasticity for Species Coexistence
- Description:
- Understanding the outcomes of interactions from assessing shoot traits has practical applications and has elucidated major ecological patterns. Roots and shoots differ in their functions and can differ in responses to abiotic and biotic stimuli. And while roots are more difficult to characterize because they tangle and are embedded in...
- Keyword:
- Plasticity, Species coexistence, Root traits, Intraspecific variation, Water stress, and Interaction
- Subject:
- Ecology, Plant sciences, and Conservation biology
- Creator:
- Foxx, Alicia J
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/28/2020
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15010 and etdadmin_upload_719313
-
- Description:
- Necessity is the mother of innovation. In the wake of the pandemic, with no flow of samples and limited fabrication techniques available, necessity demanded a new material platform and adaptable methods to make complex oxide samples worth measuring. The material platform was KTaO3 , the younger successor to the mainstay...
- Keyword:
- Magnetism, Complex Oxide, KTaO3, Superconductivity, Electrical Transport, and Cryogenic
- Subject:
- Condensed matter physics
- Creator:
- Krantz, Patrick Wallace
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1009434 and http://dissertations.umi.com/northwestern:16686
-
- Description:
- This manuscript describes and contextualizes the research I performed as a PhD student in Northwestern University. The first three chapters, on Markov chains, stochastic thermodynamics, and large deviation theory, describe three interrelated topics that serve as the background for subsequent research detailed in the next three chapters, on understanding the...
- Keyword:
- large deviation theory, thermodynamic uncertainty relations, stochastic thermodynamics, and non-equilibrium statistical mechanics
- Subject:
- Physical chemistry and Statistical physics
- Creator:
- Fu, Rueih-Sheng
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_994428 and http://dissertations.umi.com/northwestern:16629
-
- Description:
- Thermoelectric (TE) materials has been drawn broad attention given that it can enable direct conversion between thermal and electrical energies, hence is treated as a vital candidate for clean power generation as well as waste heat recycling. However, the energy conversion efficiency of TE devices used nowadays is still very...
- Keyword:
- Nanostructure, Lead Chalcogenide, Thermoelectric, and Electron Microscopy
- Subject:
- Materials Science
- Creator:
- Cai, Songting
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/06/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_829997 and http://dissertations.umi.com/northwestern:15626
-
- Description:
- This dissertation aims to develop innovative analytical methods that integrate engineering, marketing, and social science disciplines to incorporate heterogeneous consumer preferences into product design using network-based customer preference modeling. Both companies and designers frequently face difficulties in understanding and addressing customer preferences, which can result in product failure and loss...
- Keyword:
- Customer preference modeling and Computational network analysis
- Subject:
- Engineering
- Creator:
- Cui, Yaxin
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16761 and etdadmin_upload_1013692
-
- Description:
- We rely on the properties of our skeletal muscles to traverse our world, interact with objects, and complete everyday tasks. The macroscopic properties of muscles that endow us with these abilities arise from the material properties of muscle fibers and the surrounding extracellular matrix (ECM), as well as how they...
- Keyword:
- Skeletal Muscle, Decellularization, Material Properties, Ultrasound Shear Wave Elastography, and Extracellular Matrix
- Subject:
- Biomedical engineering and Biomechanics
- Creator:
- Reyna, William Eric
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_773821 and http://dissertations.umi.com/northwestern:15352
-
- Description:
- Recommender systems (RSs) have become essential tools that provide personalized recommendations to their users. These systems may consider user, item provider, and system requirements simultaneously. With the inclusion of possibly clashing considerations, there is a growing focus on solving multiple-objective recommender system (MORS) problems as efficiently as possible. The constrained...
- Keyword:
- Constrained optimization, Recommender systems, and Personal recommendations
- Subject:
- Industrial engineering
- Creator:
- Seymen, Sinan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_975783 and http://dissertations.umi.com/northwestern:16462
-
- Description:
- Historically, there have been large disparities in the degree to which different communities have access to resources and representation within society. With the increased availability of the internet and the growth of user-generated content platforms like Twitter and Wikipedia, there are opportunities to alleviate some these long-standing barriers to access...
- Keyword:
- Algorithmic Fairness, Structural Inequalities, Online Representation, and Geographic Technologies
- Subject:
- Computer science
- Creator:
- Johnson, Isaac
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_640270 and http://dissertations.umi.com/northwestern:14540
-
- Description:
- Peptides consists of a series of amino acids connected via an amide type of covalent chemical bond. A diverse field of applications such as biosensors,2 catalysis,4 and biomedicine6 include the oligomeric forms of peptides due to their genuine features comparing to other biomacromolecules. Particularly, peptides in the field of biomedical...
- Subject:
- Chemistry
- Creator:
- Choi, Wonmin
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15787 and etdadmin_upload_849083
-
- Description:
- Promyelocytic leukemia (PML) nuclear bodies act as quality control centers in the nucleus, participating in a plethora of nuclear functions. As such, PML bodies are a signature model for functional nuclear organization. PML bodies have a dynamic protein composition that responds to changing conditions of the cell. Many of the...
- Keyword:
- nuclear organization, no-go decay, mRNA surveillence, PML, Ataxin-1, and stress
- Subject:
- Molecular biology and Cellular biology
- Creator:
- Fanslow, Danielle
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_614059 and http://dissertations.umi.com/northwestern:14390
-
- Description:
- We establish the criterion for chaos in three-planet systems, for systems similar to those discovered by the Kepler spacecraft. Our main results are as follows: (i) The simplest criterion, which is based on overlapping mean motion resonances (MMRs), only agrees with numerical simulations at a very crude level. (ii) Much...
- Keyword:
- Warps, Protoplanetary Disks, Simulations, Chaos, Planets, and Dynamics
- Subject:
- Astronomy
- Creator:
- Rath, Jeremy
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16392 and etdadmin_upload_956915
-
- Description:
- Machine learning and deep learning have been proven successful across various scientific fields, such as computer vision, natural language processing, and recommendation systems. As models become more complex, with more parameters and intricate architectures, they can achieve higher prediction accuracy when trained on larger datasets. However, despite the great prediction...
- Keyword:
- Neural Network, Interpretable Machine Learning, and Function Visualization
- Subject:
- Statistics and Computational chemistry
- Creator:
- Zhang, Shengtong
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_995408 and http://dissertations.umi.com/northwestern:16632
-
- Description:
- The action of the automorphisms of a formal group on its deformation space is crucial to understanding periodic families in the homotopy groups of spheres and the unsolved Hecke orbit conjecture for unitary Shimura varieties. This action is called the Lubin-Tate action. We first show sufficient conditions for geometrically modelling...
- Keyword:
- algebraic geometry, homotopy theory, and arithmetic geometry
- Subject:
- Mathematics
- Creator:
- Ray, Catherine
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1013588 and http://dissertations.umi.com/northwestern:16756
-
- Description:
- A great deal of work has been done in recent years to construct algebraic invariants ofLegendrian knots, and their higher-dimensional analogues. Here we employ the diagram- matic calculus developed in [3], in order to develop an iterative method for computing the so-called vexillary functions of a class of Legendrian surfaces....
- Keyword:
- Moduli, Legendrian, Knot, Combinatorics, and Microlocal
- Subject:
- Mathematics
- Creator:
- Snadden, John Arthur
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16484 and etdadmin_upload_980155
-
- Description:
- Neisseria gonorrhoeae (Ng), a strict human pathogen, is the sole causative agent of gonorrhea. Gc possess a complex gene conversion system, the pilin antigenic variation system, (pilin Av), which alters the DNA sequence of the major pilin, PilE. Pilin Av results in the constant alteration of the surface exposed appendage,...
- Keyword:
- DNA recombination, Antigenic variation, and Guanine Quadruplex
- Subject:
- Microbiology and Genetics
- Creator:
- Prister, Lauren Leigh
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_684526 and http://dissertations.umi.com/northwestern:14798
-
- Description:
- This dissertation consists of three chapters that each study the interaction between government policy and real estate markets. All three chapters are connected by a broad interest in renters, landlords, and rental markets. Chapter 1 investigates the relationship between place-based policies and real estate and rental markets empirically by studying...
- Keyword:
- Rental Markets, Real Estate, and Finance
- Subject:
- Economics and Finance
- Creator:
- Hair, Christopher
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_902849 and http://dissertations.umi.com/northwestern:16077
-
- Description:
- Arising from the study of multiple ergodic averages, nilsequences and multiple correlation sequences lie at the crossroads of ergodic theory, combinatorics and number theory. We study these types of sequences along various subsequences of integers, and provide applications to ergodic theory and harmonic analysis. Our first result involves multiple correlation...
- Keyword:
- multiple correlation sequences, multiple recurrence, lacunary sequences, nilsequences, and prime numbers
- Subject:
- Mathematics
- Creator:
- Le, Anh Ngoc
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_731187 and http://dissertations.umi.com/northwestern:15040
-
- Description:
- Chapter 1 presents analysis comparing the effectiveness of two mechanisms of regulation enforcement: (1) the frequency of inspections and (2) penalties for violations. Recent policy changes regarding enforcement of mining safety regulations are exploited to quantify the effectiveness of each mechanism. It is concluded that increasing the frequency of inspections...
- Keyword:
- Skill, Bounded Rationality, Threat Effects, Slave Market, Regulation Enforcement, and Bargaining Power
- Subject:
- Economics
- Creator:
- Gmeiner, Michael William
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14716 and etdadmin_upload_668782
-
- Description:
- Photochemistry is an inherently interdiscplinary field where very large energies are leveraged for the making and breaking of bonds. My work has broadly dealt with various strategies to control how energy delivered by light can be channeled into useful functions. I developed a strategy to control the chemo- and stereo-selectivity...
- Subject:
- Organic chemistry
- Creator:
- Eckdahl, Christopher Todd
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_910914 and http://dissertations.umi.com/northwestern:16124
-
- Description:
- Research on how sleep contributes to memory has blossomed in recent years. These studies have generally focused on whether or not sleep impacts various types of memory independently. An open question is whether sleep interactively influences different memory types. My research focuses on two types of memory—specificity and generalization. Whereas...
- Keyword:
- memory, sleep, generalization, memory consolidation, and targeted memory reactivation
- Subject:
- Cognitive psychology, Psychobiology, and Neurosciences
- Creator:
- Witkowski, Sarah (Sadie)
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/15/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15250 and etdadmin_upload_763727
-
- Description:
- Autism spectrum disorder (ASD) and intellectual disability (ID) are two of the most highly prevalent neurodevelopmental disorders (NDDs), each affecting roughly 2% of the population. Despite the need for therapies, few exist due to a myriad of challenges, such as the complex underlying genetic etiology and historic inaccessibility of neural...
- Keyword:
- PACS1 syndrome, Induced pluripotent stem cells, Single-cell RNA sequencing, Intellectual disability, Cerebral organoids, and Autism spectrum disorder
- Subject:
- Molecular biology and Neurosciences
- Creator:
- Rylaarsdam, Lauren Elizabeth
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_984633 and http://dissertations.umi.com/northwestern:16538
-
- Description:
- Fibrosis is a chronic pathology which commonly develops after chronic inflammation. Different specific kinds of inflammation have been linked to fibrosis across various tissues. When specifically occurring in the prostate, fibrosis can lead to urinary dysfunction. Prostate conditions that involve inflammation have also been linked to both prostate fibrosis and...
- Keyword:
- Inflammation, Prostate, Fibrosis, Urinary Dysfunction, Immunology, and Type 2 cytokines
- Subject:
- Immunology
- Creator:
- Bell-Cohn, Ashlee
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_742505 and http://dissertations.umi.com/northwestern:15093
-
- Description:
- In this thesis we study the geometric limits under degree growth of Julia sets and filled Julia sets for complex polynomials with a unique critical point at $z = 0$. Specifically, for $c \in \mathbb{S}^1$, we are interested in the limit of the associated sequence of Julia sets $J(f_{n,c})$ in...
- Subject:
- Mathematics
- Creator:
- Jensen, Signe Emalia
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15689 and etdadmin_upload_840531
-
- Description:
- Digitization has led to dramatic cost reductions and reshaped both what and how products are sold. This dissertation examines the impact of digitization on the behavior of market intermediaries that bring together producers and consumers. Our empirical context is the transition from 35mm film to digital cinema technologies in the...
- Keyword:
- Product Variety, Concentration, and Digitization
- Subject:
- Marketing and Economics
- Creator:
- Yang, Joonhyuk
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_736303 and http://dissertations.umi.com/northwestern:15056
-
- Description:
- Inflammasomes are intracellular multiprotein signaling complexes that link Pathogen Associated and Danger Associated Molecular Patterns (PAMPs and DAMPs) by Pattern Recognition Receptors (PRRs) to the activation of Caspase-1, leading to the secretion of pro-inflammatory cytokines interleukin (IL)-1β and IL-18, and the induction of pyroptosis. Nucleotide-binding oligomerization domain (NOD)-like containing a...
- Keyword:
- Inflammation, Inflammasome, Gout, Innate immune response, NLRP3, and NLRP11
- Subject:
- Biology
- Creator:
- Gangopadhyay, Anu
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15043 and etdadmin_upload_731489
-
- Description:
- The histone methyltransferase DOT1L methylates lysine 79 (K79) on histone H3 and is implicated in active transcription. Here we show that DOT1L is overexpressed in Prostate cancer (PCa) and is associated with poor clinical outcome. Genetic and chemical inhibition of DOT1L selectively impaired viability of androgen receptor (AR)-signaling competent PCa...
- Keyword:
- Prostate Cancer, DOT1L, and Epigenetics
- Subject:
- Molecular biology and Oncology
- Creator:
- Vatapalli, Rajita
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/29/2020
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14971 and etdadmin_upload_714534
-
- Description:
- The integration of field-programmable gate arrays (FPGAs) into large scale computing systems is gaining attention. In these systems, real-time data handling for networking, tasks for scientific computing, and machine learning can be executed with customized datapaths on reconfigurable fabric within heterogeneous compute nodes. At the same time, high-level synthesis (HLS)...
- Keyword:
- thermal-aware design, thermal modeling, dynamic monitoring, high-performance computing, task placement, and OpenCL
- Subject:
- Computer engineering
- Creator:
- Luo, Yingyi
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_774615 and http://dissertations.umi.com/northwestern:15358
-
- Description:
- Wearable visual systems, such as ego-centric wearable cameras, have failed to integrate into everyday life. We have witnessed the abandonment of wearable visual systems as consumer devices (e.g., Google Glass) and as research tools (e.g., SenseCam). While it is natural for some technologies to die out, visual wearable systems are...
- Subject:
- Computer science
- Creator:
- Alharbi, Rawan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_928895 and http://dissertations.umi.com/northwestern:16256
-
- Description:
- Multistage optimization is a prominent modeling tool to solve a broad range of dynamic decision-making problems in the presence of uncertainty. However, computing optimal policies is intractable, since they are obtained by considering all possible realizations of uncertainties and subsequent future decisions over time. To overcome these challenges, we present...
- Keyword:
- Robust Optimization, Multistage Optimization, Dynamic Policies, Distributionally Robust Optimization, and Adaptive Policies
- Subject:
- Industrial engineering and Operations research
- Creator:
- Han, Eojin
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15200 and etdadmin_upload_756991
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- Description:
- Thinkers attempting to challenge existing conceptions of political life often find that they encounter limitations in dominant modes of spectatorship and communication. If popular audiences are unsuitably oriented toward the presentation of certain content, this introduces a fundamental obstacle for political theoretic efforts to shape ideas and interactions. This dissertation...
- Keyword:
- Machiavelli, Arendt, Rhetoric, History of Political Thought, Rousseau, and Democratic Theory
- Subject:
- Political science
- Creator:
- Litvin, Boris
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14619 and etdadmin_upload_661977
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- Description:
- Listeners can experience strong and often positive identification with music. Contemporary research has emphasized the importance of a listener’s own identity, including their sense of self and their desires, when forming such identifications. However, acknowledgments of the listener’s role in the listening experience have failed to productively engage discussions of...
- Keyword:
- Agency, Musical Empathy, Empathy, Music Analysis, Musical Agency, and Subjectivity
- Subject:
- Cognitive psychology, Music theory, and Social psychology
- Creator:
- Leaman, Aubrey
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_917201 and http://dissertations.umi.com/northwestern:16158
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- Description:
- Chemical modifications of oligonucleotides (ONs) have advanced these molecules towards clinical approvals. On their own, native ONs have poor pharmacokinetic properties, such as rapid degradation by nucleases and poor cell uptake, which limit their potential therapeutic applications. Chemical modifications of ONs can increase their stability, alter their interactions with cells,...
- Subject:
- Chemistry
- Creator:
- Skakuj, Kacper
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_769294 and http://dissertations.umi.com/northwestern:15317
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- Description:
- Mortgage brokers originate a large share of residential real estate lending. Exploiting state-level regulatory changes to local entry costs I am able to study the effect on credit quality and access. Using data from a major mortgage lender in the run up to the financial crisis I study how the...
- Subject:
- Finance
- Creator:
- Stephenson, Harvey Hugh
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14642 and etdadmin_upload_662464
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- Description:
- Excess loading of reactive nitrogen and phosphorus into the environment from human activities has resulted in widespread eutrophication and the degradation of surface water quality and wildlife habitat. Wastewater is the dominant point source of nutrient loading into waterways, and thus represents a critical opportunity for treatment and prevention of...
- Keyword:
- wastewater, comammox, anammox, enhanced biological phosphorus removal (EBPR), nitritation-denitritation, and nitrogen
- Subject:
- Environmental engineering
- Creator:
- Roots, Paul
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15107 and etdadmin_upload_743134
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- Description:
- Early life adversity predicts greater health risk in later life across multiple outcomes, including cardiovascular disease (CVD) and all-cause mortality. While biological pathways are incompletely understood, evidence is increasingly highlighting immune function, specifically chronic inflammation, which is implicated in cardiometabolic diseases, certain cancers, and all-cause mortality. Links between early adversity...
- Subject:
- Physical anthropology
- Creator:
- Aronoff, Jacob
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_945998 and http://dissertations.umi.com/northwestern:16356
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- Description:
- Despite the increasing interest in biogenic secondary organic aerosols (SOAs), their role in the climate system remains the greatest source of uncertainty in global models. Cloud formation, critical for the net cooling effect provided by cloud cover, is dependent on the abundance of SOA particles and their ability to activate...
- Subject:
- Physical chemistry, Atmospheric chemistry, and Chemistry
- Creator:
- Bellcross, Aleia
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16628 and etdadmin_upload_993914
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- Description:
- The purpose of this multiple-case study was to examine the lived experiences of current collegiate music education majors, both students from under-represented minorities and their well-represented peers, with attention to racial/ethnic identity and social class. Dyads of current music education students at 8 separate colleges/universities—a student from an under-represented racial...
- Keyword:
- music teacher education, intersectionality, race, social class, and music education
- Subject:
- Music education and Sociology
- Creator:
- Berglin, Jacob Axel
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_627573 and http://dissertations.umi.com/northwestern:14480
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- Description:
- Macrophages are innate immune cells that are traditionally thought to be specialists in phagocytosis. More recent evidence suggest that macrophages reside in nearly every organ and readily adapt to local microenvironmental signals, leading to highly plastic phenotypes across and within tissues. Therefore, rather than treating it as a homogenous cell...
- Keyword:
- macrophage, bioinformatics, and NGS
- Subject:
- Bioinformatics and Biology
- Creator:
- Chen, Shang-Yang
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16027 and etdadmin_upload_900059
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- Description:
- Unrestrained urban growth combined with the increase in the intensity and frequency of precipitation events, due to climate change, has become a major challenge for urban green spaces. Urban sprawl increases ecosystem degradation and the vulnerability of cities to floods as a result of excess stormwater runoff and non-point source...
- Keyword:
- human impacts, ecosystem services, green roof, stormwater runoff, green infrastructure, and wetland
- Subject:
- Environmental science and Environmental engineering
- Creator:
- Hernandez Gonzalez, Liliana Maria
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15553 and etdadmin_upload_818005
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- Description:
- One of the fundamental questions in developmental biology is how a single cell gives rise to a complex organism. More specifically, how a totipotent egg divides into cells that become increasingly restricted in their potential. Development is a process of increasingly restricted cellular potential, and here I home in on...
- Keyword:
- Xenopus, Pluripotency, Neural Default Model, BMP, Smads, and Activin
- Subject:
- Biology and Developmental biology
- Creator:
- Johnson, Kristin Lorette
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16347 and etdadmin_upload_945075
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- Description:
- This project centers set design as the primary aesthetic, economic, and sociopolitical driver of the sitcom genre’s emergence and development during the first half of the twentieth century. My work treats sitcom set design as a category of historical architecture that can be (and has been) mapped, toured, built, and...
- Keyword:
- radio, television, house, sitcom, domestic, and design
- Subject:
- American history, Mass communication, and Architecture
- Creator:
- LaPlaca, Laura N
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_742942 and http://dissertations.umi.com/northwestern:15104
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- Description:
- Van der Waals, or layered, materials offer a flexible platform to tune properties via exfoliation down to the single- or few-layer limit; they are at the forefront of cutting-edge materials science and engineering research because of the innumerable ways to tune materials as a function of thickness or composition. Due...
- Keyword:
- liquid-phase exfoliation, van der Waals materials, ambient-reactive, two-dimensional materials, and solution processing
- Subject:
- Materials Science
- Creator:
- Lam, David
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_913984 and http://dissertations.umi.com/northwestern:16137