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- Description:
- Biological systems comprise diverse collections of cellular and non-cellular components with intricate relationships and dynamic interactions. To gain system-level understanding, we must be able to accurately model these systems, both experimentally and computationally. Agent-based models (ABMs) in particular are a uniquely intuitive, modular, and flexible framework capable of supporting multi-scale,...
- Keyword:
- emergent behavior, systems biology, and agent-based modeling
- Subject:
- Biology, Chemical engineering, and Computer science
- Creator:
- Yu, Jessica
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_743010 and http://dissertations.umi.com/northwestern:15106
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- Description:
- In this dissertation I examine issues related to uncertainty and robustness in game theory. In Chapter 1 a strategic setting is analyzed where players face Knightian uncertainty about the strategic choices of their opponents. That is, in contrast to the usual Bayesian framework and in line with experimental evidence, players...
- Subject:
- Economics and Economic theory
- Creator:
- Ziegler, Gabriel
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15108 and etdadmin_upload_743149
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- Description:
- The ever growing desire for accurate estimation and efficient learning necessitates the efforts to quantitatively characterize uncertainties for models. In this thesis, four problems pertaining to uncertainty quantification are discussed: A sequential stopping framework of constructing fixed-precision confidence regions is proposed for a class of multivariate simulation problems where variance...
- Keyword:
- Ranking and Selection, Reinforcement Learning, Statistical Learning, Stochastic Gradient Descent, and Uncertainty Quantification
- Subject:
- Applied mathematics, Statistics, and Computer science
- Creator:
- Zhu, Yi
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15080 and etdadmin_upload_741745
-
- Description:
- As conventional electronic materials approach the device scaling limits, new types of materials and structures have been examined for potential use in future electronic and optoelectronic applications including transistors, light emitting diodes, and solar cells. In recent years, atomically thin or two-dimensional (2D) transition metal dichalcogenide (TMD) materials have emerged...
- Keyword:
- electron microscopy, heterostructures, electronic properties, grain boundaries, 2d materials, and interfaces
- Subject:
- Materials Science
- Creator:
- MURTHY, AKSHAY ARUN
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_730816 and http://dissertations.umi.com/northwestern:15038
-
- Description:
- Periodic exposure to light and dark as a result of rotation of the Earth have served as a major evolutionary pressure to partition divergent biological processes to different phases of the day. Mammals display periods of activity/inactivity, wake/sleep, and feeding/fasting during distinct portions of the day. In mammals, these activities...
- Subject:
- Molecular biology, Medicine, and Endocrinology
- Creator:
- Levine, Daniel C
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15034 and etdadmin_upload_727063
-
- Description:
- Technological innovation is a key determinant of economic growth, and my dissertation is to understand the links between the investment of technological innovation and financial markets, with a focus on how the macroeconomic environment interacts with and is influenced by the financial constraints facing firms. Chapter one investigates the links...
- Keyword:
- Macroeconomic, Innovation, Debt, Technology, Economic Growth, and Finance
- Subject:
- Finance
- Creator:
- Huang, Qiushi
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15047 and etdadmin_upload_732371
-
- Description:
- Brain network organization, the emergence of cognition, and the accumulation of neurodegenerative pathology are interwoven concepts frequently studied under the umbrella of behavioral neurology, neuropsychiatry, neuropsychology, and neuropathology. One approach to studying the organization of cognitive processes is to study those with selective deficits in such networks. To understand how...
- Keyword:
- primary progressive aphasia, cortical atrophy, neuroimaging, Alzheimer disease, and brain networks
- Subject:
- Pathology, Medical imaging, and Neurosciences
- Creator:
- Martersteck, Adam Christopher
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_743337 and http://dissertations.umi.com/northwestern:15111
-
- Description:
- This dissertation is composed by three chapters. Chapter one is about productivity hysterisis in the U.S. after the Great Recession. The United States has been experiencing a slowdown in productivity growth for more than a decade. I exploit geographic variation across U.S. Metropolitan Statistical Areas (MSAs) to investigate the link...
- Subject:
- Economics
- Creator:
- Carreno-Garcia, Jose
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_740053 and http://dissertations.umi.com/northwestern:15069
-
- Description:
- Humans are prodigious learners. One of our most powerful learning tools is the ability to detect and transfer relational similarities between items and events, despite their perceptual differences. Previous research has found that the roots of this ability extend into infancy. As early as three months of age, infants can...
- Keyword:
- cognitive development, infant development, language development, and relational learning
- Subject:
- Cognitive psychology and Developmental psychology
- Creator:
- Anderson, Erin M
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15068 and etdadmin_upload_739995
-
- Description:
- Single-molecule localization microscopy (SMLM) has significantly stimulated the development of methods to quantitatively visualize and characterize biomolecules in vitro and in situ. SMLM is a class of super-resolution microscopy (SRM) techniques, which exploits the “on-off” switching of individual fluorescent molecules to estimate their location with nanometer precision and offers spatial...
- Keyword:
- single-molecule localization microscopy, spectroscopy, super-resolution microscopy, and quantitative imaging
- Subject:
- Biomedical engineering
- Creator:
- Davis, Janel Lesedi
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15048 and etdadmin_upload_733040
-
- Description:
- In Due Time: Performance and the Psychic Life of Black Debt analyzes how routine modes of debt and indebtedness restrict black women’s behavior across the everyday sphere and their subsequent engagement with both aesthetic and everyday performance to dismantle such routines. Modes of indebtedness are characteristic of racial capitalism and...
- Keyword:
- Gesture, Black Women, Duration & Time, Debt, Performance, and Queer
- Subject:
- Women's studies, LGBTQ studies, and Black studies
- Creator:
- De Berry, Misty
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_743674 and http://dissertations.umi.com/northwestern:15117
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- Description:
- Sound is one of the most important mediums to understand the environment around us. Identifying a sound event in prerecorded audio (such as a police siren, a dog bark, or a creaking door in soundscapes) leads to a better understanding of the context where the sound events occurred. To do...
- Keyword:
- Human-in-the-loop interface, Sound event detection, Sound event annotation, Audio signal processing, and Machine learning
- Subject:
- Artificial intelligence and Computer science
- Creator:
- Kim, Bongjun
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_739320 and http://dissertations.umi.com/northwestern:15064
-
- Description:
- The commercial success of personal computing has led to the rapid creation and proliferation of diverse electronic systems including desktops, laptops, tablets, mobile devices, and embedded systems. For the past five decades, silicon has served as the base material for computing electronics. However, with increasing demand for unconventional electronics (e.g.,...
- Keyword:
- Amplifiers, Random number generator, Internet of Things, Transistors, Electronic, and Carbon nanotubes
- Subject:
- Electrical engineering and Materials Science
- Creator:
- Gaviria Rojas, William A
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_743198 and http://dissertations.umi.com/northwestern:15110
-
- Description:
- In this dissertation I analyze how population aging and political considerations can affect the conduct of fiscal policy and the management of sovereign debt. In Chapter 1 I focus on the impact of an aging population. In Chapter 2 I consider the effects of political uncertainty. How an aging population...
- Keyword:
- Population aging, Sovereign debt, Political uncertainty, and Fiscal policy
- Subject:
- Economics
- Creator:
- Magistretti, Giacomo
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_743431 and http://dissertations.umi.com/northwestern:15113
-
- Description:
- In Chapter 1 I characterize sharp bounds on treatment effects under data combination with instrumental variables. Data combination in this paper refers to having multiple samples drawn from the same population in which observations cannot be linked across samples. I allow for subsets of the outcome, treatment, instrument and covariates...
- Subject:
- Economics
- Creator:
- Lee, Ryan Alan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_743663 and http://dissertations.umi.com/northwestern:15115
-
- Description:
- The basal ganglia are a remarkably complicated and interconnected tangle of subcortical nuclei whose exact function and composition are hotly debated to this day. What is plainly obvious, however, is that loss of dopaminergic modulation in the basal ganglia, as is the case in Parkinson’s disease (PD) following the progressive...
- Keyword:
- in vivo electrophysiology, anesthesia, basal ganglia, optogenetics, and 6-hydroxydopamine
- Subject:
- Neurosciences
- Creator:
- Kovaleski, Ryan Francis
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_720363 and http://dissertations.umi.com/northwestern:15020
-
- Description:
- Language is a hallmark of human cognition—a rich and flexible method of representing the world around us. As such, language provides an invaluable resource to human infants: a way of gaining insight into the representations that guide adult cognition. In this dissertation, I explore how language influences infants’ cognition as...
- Keyword:
- categorization, development, language, infant, learning, and cognition
- Subject:
- Cognitive psychology
- Creator:
- LaTourrette, Alexander Scott
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_732252 and http://dissertations.umi.com/northwestern:15046
-
- Description:
- China’s e-commerce development tells a story of how, under a strong authoritarian state, non-state-owned startup companies grew rapidly without state support and transformed many aspects of state-society relations. Combining qualitative and quantitative methods, this dissertation makes a vital early attempt to uncover the impact of e-commerce development on China’s state-society...
- Keyword:
- government-business relations, institutional change, Chinese political economy, informal labor, and e-commerce industry
- Subject:
- Political science
- Creator:
- SHAO, YIXUE
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_742274 and http://dissertations.umi.com/northwestern:15088
-
- Description:
- Chapter 1 proposes a parsimonious two-country, two-good, and complete-market model featuring heterogeneous beliefs to address the Backus-Smith, volatility, and forward premium puzzles in international finance. The presence of the time-varying difference in beliefs has direct and indirect effects on equilibrium exchange rates. The direct effect appears as a wedge in...
- Subject:
- Finance
- Creator:
- XIa, Shixiang
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15074 and etdadmin_upload_741127
-
- Description:
- In recent years Additive Manufacturing (also known as 3D printing) processes have risen in use within research and industry to create complex, custom parts, which would be otherwise too expensive or even impossible to fabricate via conventional manufacturing methods. While originated as a tool for rapid prototyping, the improvements in...
- Keyword:
- Scaffolds, Fabrication Accuracy, Biomedical, and Additive Manufacturing
- Subject:
- Mechanical engineering
- Creator:
- Ware, Henry Oliver Tenadooah
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15077 and etdadmin_upload_741389