The purpose of this study was to examine the effects of applied improvisation and composition assignments that were related to and reinforcing of curriculum content on fifth-grade students' ability to sight-read traditional music notation, ability to learn to play the soprano recorder, and understanding of music theory. Specifically, the research...
Kinesin-1 is a motor protein that transports cargo along microtubules. Inside cells, the majority of kinesin-1 is regulated to conserve ATP and ensure its proper intracellular distribution and coordination with other motors. Regulated kinesin-1 is folded in half, and interactions between coiled-coil regions near the N-terminal enzymatically active heads and...
Inflammasomes are signaling complexes that link the recognition of pathogen and danger associated molecular patterns (PAMPs and DAMPs) by cytosolic pattern-recognition receptors (PPRs) to the activation of Caspase-1, leading to the release of the pro-inflammatory cytokines interleukin (IL)-1 and IL-18, and the induction of pyroptosis. In addition to the canonical...
Coronary magnetic resonance angiography (MRA) is emerging as a promising method for noninvasive diagnosis of coronary artery diseases. Nonetheless, acquisition of large-coverage high-resolution coronary artery images requires free-breathing acquisition. Accurately measuring and correcting respiratory motion has been one of the major challenges to coronary MRA. Diaphragmatic navigator (NAV), the current...
This paper aims to understand how international legal harmonisation impacts legal certainty in countries where most of the economy is informal by examining how OHADA laws have been applied in Cameroon. It describes how the OHADA laws were developed internationally and applied locally and how the actors in two spheres...
This dissertation is composed of three chapters, each contributing to different aspects of the literature of partially identified econometric models.
In the first chapter, I introduce a bootstrap procedure to perform inference in the class of partially identified econometric models defined by finitely many moment equalities and inequalities. I provide...
A multicomponent bimodal poly(vinyl acetate) (PVAc) polymer composite has been scientifically designed to increase biaxial plastic flow stabilization for the achievement of large biaxial deformations. For this, a systems-based approach was used for the computational materials design of a high performance bubblegum whose mean in-vivo bubble diameter exceeds that of...
This dissertation aims to: 1) characterize the range of beliefs museum practitioners have about racial, ethnic, and cultural diversity; 2) their understanding of the role of race, culture, and ethnicity in minoritized learners’ sensemaking; and 3) the areas of tension and symmetry between practitioners’ values and their perception of their...
The actions of luteinizing hormone (LH) to induce ovulation and luteinization of preovulatory follicles are mediated principally by activation of cAMP-dependent protein kinase (PKA) in granulosa cells. PKA activity is targeted to specific cellular locations by A-kinase anchoring proteins (AKAPs). I previously showed that follicle-stimulating hormone (FSH) induces expression of...
Fusion of biological membranes is dictated by the interaction between specialized membrane proteins and the lipid bilayer. Parainfluenza virus 5 (PIV5) mediates fusion using two surface glycoproteins: the fusion protein (F) and the attachment protein hemagglutinin-neuraminidase (HN). Activation of membrane fusion of PIV5 typically occurs at neutral pH, and involves...