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  1. A Brain-Machine Interface for Regaining Control of a Paralyzed Arm: A Primate Model of Cortically Controlled Functional Electrical Stimulation

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    Description: A critical challenge in improving the quality of life for spinal cord injury survivors is to restore the capacity to grasp and manipulate objects. While progress has been made to restore hand function by using functional electrical stimulation (FES) to activate muscles, providing the means to control the multiple degrees...
    Keyword: Engineering and Biomedical
    Subject: Biomedical Engineering
    Creator: Eric Pohlmeyer
    Owner: Scholarly Digital Publishing
    Date Uploaded: 09/18/2018
    Date Modified: 09/18/2018
    Date Created: 2008-07-28
    Rights: In Copyright
    Resource Type: Dissertation
  2. Tissue transglutaminase: A new method of facilitating hydrogel formation for cartilage regeneration and cartilage surface modification

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    Description: Articular cartilage is a type of connective tissue that protects the underlying bone from the compressive forces of daily activities. When cartilage is damaged via a traumatic event, chondral defects are formed and require medical intervention. However, current treatments are of inconsistent efficacy and only benefit a subset of patients....
    Keyword: hydrogel, transglutaminase, peptide, biomaterials, cartilage, and drug
    Subject: Biomedical Engineering
    Creator: Marsha Elizabeth Ritter Jones
    Owner: Scholarly Digital Publishing
    Date Uploaded: 09/12/2018
    Date Modified: 09/12/2018
    Date Created: 2008-05-06
    Rights: In Copyright
    Resource Type: Dissertation
  3. Investigation of the Effects of Caffeine Using Calibrated BOLD

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    Description: Caffeine is the most widely consumed methylxanthine, primarily found in beverages. As a nonspecific antagonist to adenosine, caffeine binds to both A1 and A2A adenosine receptors to increase neural activity and decrease cerebral blood flow, which allows it to alter neurovascular coupling. However, there has been much debate about the...
    Keyword: neurovascular coupling, caffeine, ASL, and calibrated BOLD
    Subject: Biomedical Engineering
    Creator: Yufen Chen
    Owner: Scholarly Digital Publishing
    Date Uploaded: 09/11/2018
    Date Modified: 09/11/2018
    Date Created: 2008-04-25
    Rights: In Copyright
    Resource Type: Dissertation
  4. Bioadhesion of Mussels and Geckos: Molecular Mechanics, Surface Chemistry, and Nanoadhesives

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    Description: The adhesive strategies of living creatures are diverse, ranging from temporary to permanent adhesions with various functions such as locomotion, self-defense, communication, colony formation, and so on. The classic example of temporary adhesion is the gecko, which is known for its ability to walk along vertical and even inverted surfaces;...
    Keyword: layer-by-layer, dopamine, gecko, material-independent, Mussel, and single-molecule
    Subject: Biomedical Engineering
    Creator: Haeshin Lee
    Owner: Scholarly Digital Publishing
    Date Uploaded: 09/11/2018
    Date Modified: 09/11/2018
    Date Created: 2008-03-27
    Rights: In Copyright
    Resource Type: Dissertation
  5. Functional MRI of Eyeblink Conditioning in the Rabbit

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    Description: Classical conditioning has been well studied over the last century as a method for investigating learning and memory. The rabbit eyeblink response is commonly used as a basis for such studies, and combined with lesions or electrophysiological recordings has provided a well-controlled paradigm for investigating the neurobiological mechanisms underlying learning...
    Keyword: Biomedical Engineering
    Subject: Biomedical Engineering
    Creator: Michael J Miller
    Owner: Scholarly Digital Publishing
    Date Uploaded: 09/10/2018
    Date Modified: 09/10/2018
    Date Created: 2008-05-08
    Rights: In Copyright
    Resource Type: Dissertation
  6. Surface Modification with Antifouling Polymers Composed of Polypeptoids and Mussel Adhesive-Inspired Peptides

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    Description: Biological fouling of surfaces is problematic for many medical applications because proteins, cells and bacteria can impair the function of devices and lead to catastrophic complications. Numerous strategies exist for reducing fouling in physiological environments; the strategy described in this thesis focuses on the modification of substrates with poly-N-substituted glycine...
    Keyword: polypeptoids, nonfouling, mussel adhesive proteins, surface modification, Antifouling, and surface characterization
    Subject: Biomedical Engineering
    Creator: Andrea Ruth Statz
    Owner: Scholarly Digital Publishing
    Date Uploaded: 09/08/2018
    Date Modified: 09/08/2018
    Date Created: 2008-05-05
    Rights: In Copyright
    Resource Type: Dissertation
  7. Development and Application of Poly(diol citrates) and a Novel Bioreactor System for Vascular Tissue Engineering

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    Description: Despite three decades of intense research into small diameter blood vessel tissue engineering, constructs developed to date lack the elastin necessary for long term patency and the prevention of aneurysms. The suboptimal biochemical composition suggests that new biochemical and mechanical culture methods must be developed. In addition, current biomaterials for...
    Keyword: biomaterials, vascular graft, bioreactor, tissue engineering, and elastomer
    Subject: Biomedical Engineering
    Creator: Antonio Roy Webb
    Owner: Scholarly Digital Publishing
    Date Uploaded: 09/06/2018
    Date Modified: 09/06/2018
    Date Created: 2008-03-13
    Rights: In Copyright
    Resource Type: Dissertation
  8. Quantifying Structural and Activation-dependent Contributions to Short-range Stiffness of Skeletal Muscles

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    Description: Short-range stiffness (SRS) of a skeletal muscle describes the muscle's capability to resist external perturbations before the nervous system can intervene. Knowledge of the SRS of individual muscles is critical in understanding their contributions to single joint stiffness and whole limb stability. While the dependence of SRS on muscle force...
    Keyword: short-range stiffness, connective tissues, muscle stiffness, muscle modeling, and tendon mechanical property
    Subject: Biomedical Engineering
    Creator: Lei Cui
    Owner: Scholarly Digital Publishing
    Date Uploaded: 08/30/2018
    Date Modified: 08/30/2018
    Date Created: 2007-08-30
    Rights: In Copyright
    Resource Type: Dissertation
  9. Independent Neural Control of Motions and Forces

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    Description: During interactions with our environment we must incorporate information about the mechanical properties of obstacles into our motor actions. Fundamental to these behaviors is the ability to simultaneously control movements of the hand while regulating the interaction forces that arise from contact with the environment. Although the neural control of...
    Keyword: computational neuroscience, transcranial magnetic stimulation, motor learning, psychophysics, and haptics
    Subject: Biomedical Engineering
    Creator: Vikram Singh Chib
    Owner: Scholarly Digital Publishing
    Date Uploaded: 08/28/2018
    Date Modified: 08/28/2018
    Date Created: 2007-12-03
    Rights: In Copyright
    Resource Type: Dissertation
  10. Investigation of Muscle Synergies as a Control Paradigm for Myoelectric Devices

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    Description: A need exists to increase the functionality of myoelectric prostheses without increasing the mental requirement of operation. Implantable myoelectric sensors have made it possible to record multiple muscle activities with high fidelity. Given this high dimensionality of inputs, what is the best way of implementing control? Muscle synergies have been...
    Keyword: dimensionality reduction, muscle synergy, prosthesis, hand, myoelectric control, and EMG
    Subject: Biomedical Engineering
    Creator: Abidemi Bolu Ajiboye
    Owner: Scholarly Digital Publishing
    Date Uploaded: 08/27/2018
    Date Modified: 08/27/2018
    Date Created: 2007-12-04
    Rights: In Copyright
    Resource Type: Dissertation