Of the half million new cases of invasive cervical cancer (ICC) reported globally each year, over 80% occur in Low-and Middle-Income Countries (LMICs)1. Nigeria is one of these countries with a huge burden of ICC incidence and mortality.2 As reported in the Global Burden of Cancer 2013, cervical cancer is...
DNA methylation in repetitive elements (RE) suppresses their mobility and maintains genomic stability, and decreases in it are frequently observed in tumor and/or surrogate tissues. Averaging methylation across RE in the genome is widely used to quantify global methylation. Methylation of RE in humans is considered a surrogate for global...
While literature indicates that fewer than half of older adults aged 65 years or older receive high quality end-of-life care, less is known about the quality of end-of-life care experienced by the segment of that population with multiple chronic conditions (MCC). Drawing upon the Teno Model of high quality end-of-life...