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- Description:
- This manuscript describes and contextualizes the research I performed as a PhD student in Northwestern University. The first three chapters, on Markov chains, stochastic thermodynamics, and large deviation theory, describe three interrelated topics that serve as the background for subsequent research detailed in the next three chapters, on understanding the...
- Keyword:
- large deviation theory, thermodynamic uncertainty relations, stochastic thermodynamics, and non-equilibrium statistical mechanics
- Subject:
- Physical chemistry and Statistical physics
- Creator:
- Fu, Rueih-Sheng
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_994428 and http://dissertations.umi.com/northwestern:16629
-
- Description:
- This dissertation aims to develop innovative analytical methods that integrate engineering, marketing, and social science disciplines to incorporate heterogeneous consumer preferences into product design using network-based customer preference modeling. Both companies and designers frequently face difficulties in understanding and addressing customer preferences, which can result in product failure and loss...
- Keyword:
- Customer preference modeling and Computational network analysis
- Subject:
- Engineering
- Creator:
- Cui, Yaxin
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16761 and etdadmin_upload_1013692
-
- Description:
- Machine learning and deep learning have been proven successful across various scientific fields, such as computer vision, natural language processing, and recommendation systems. As models become more complex, with more parameters and intricate architectures, they can achieve higher prediction accuracy when trained on larger datasets. However, despite the great prediction...
- Keyword:
- Neural Network, Interpretable Machine Learning, and Function Visualization
- Subject:
- Statistics and Computational chemistry
- Creator:
- Zhang, Shengtong
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_995408 and http://dissertations.umi.com/northwestern:16632
-
- Description:
- The action of the automorphisms of a formal group on its deformation space is crucial to understanding periodic families in the homotopy groups of spheres and the unsolved Hecke orbit conjecture for unitary Shimura varieties. This action is called the Lubin-Tate action. We first show sufficient conditions for geometrically modelling...
- Keyword:
- algebraic geometry, homotopy theory, and arithmetic geometry
- Subject:
- Mathematics
- Creator:
- Ray, Catherine
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1013588 and http://dissertations.umi.com/northwestern:16756
-
- Description:
- Despite the increasing interest in biogenic secondary organic aerosols (SOAs), their role in the climate system remains the greatest source of uncertainty in global models. Cloud formation, critical for the net cooling effect provided by cloud cover, is dependent on the abundance of SOA particles and their ability to activate...
- Subject:
- Physical chemistry, Atmospheric chemistry, and Chemistry
- Creator:
- Bellcross, Aleia
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16628 and etdadmin_upload_993914
-
- Description:
- Although elevated stress and dietary change have each been associated with metabolic health decline for resettled populations in the Global North, considerably less attention is paid to the links between these two biosocial pathways. Addressing these linkages can elucidate interrelated diet and stress mechanisms that affect population health disparities over...
- Keyword:
- biospychosocial stress, social determinants of health, health inequity, social ecologies of eating, and migration
- Subject:
- European studies, Food science, and Public health
- Creator:
- Koselka, Elizabeth Palmer DeVine
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1014377 and http://dissertations.umi.com/northwestern:16783
-
- Description:
- Submodularity is a well-known concept in integer programming and combinatorial optimization. Submodular set functions capture the diminishing returns phenomenon, which has wide-ranging applications in various domains. Typically, a submodular set function models the utility of homogenous items selected from a single ground set. Selecting an item or not is naturally...
- Keyword:
- mixed-integer programming, polyhedral, convex hull, and nonlinear optimization
- Subject:
- Operations research
- Creator:
- Yu, Qimeng
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1013578 and http://dissertations.umi.com/northwestern:16754
-
- Description:
- Controlled delivery of foreign cargo into cells is a critical step in many biological studies and in cell engineering and analysis workflows. Recent advances in micro and nanotechnology, specifically in microfluidics and microfabrication have added significantly to the precision, accuracy, resolution and throughput of cell manipulation and analysis pipelines. These...
- Subject:
- Mechanical engineering
- Creator:
- Pathak, Nibir
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16641 and etdadmin_upload_997980
-
- Description:
- Metalloenzymes catalyze remarkable reactions in Nature using transition metal ions. Common earth-abundant metals like copper, iron, zinc, and magnesium catalyze reactions that are the basis of life. These metal sites lend their chemistries to facilitate these reactions, making studying the structure and properties important in understanding the enzymes' abilities and...
- Keyword:
- Metalloenzymes, Computations, Biochemistry, Physical Chemistry, Inorganic Chemistry, and Paramagnetic Spectroscopy
- Subject:
- Chemistry
- Creator:
- Jodts, Richard Jacob
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16659 and etdadmin_upload_1001514
-
- Description:
- For many years silicon tethers have been used to increase yields and control the stereochemical and regiochemical outcomes of coupling reactions. Silicon tethers may be incorporated into a wide range of reaction types including alkene metathesis, cycloadditions, and glycosylations. This thesis focuses on the development of the use of silicon...
- Subject:
- Organic chemistry
- Creator:
- Caravana, Aidan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16637 and etdadmin_upload_996558
-
- Description:
- Drying oils have been used as a binding medium for oil paints since the 15th century. These oil paints transition from a liquid-like paste to a solid-like film as a result of crosslinks forming between the oil molecules. These reactions have been extensively studied chemically, but other material properties are...
- Keyword:
- ATR-FTIR, Linseed oil, Drying oils, and Mechanical Properties
- Subject:
- Polymer chemistry and Materials Science
- Creator:
- dePolo, Gwen Ellen
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16730 and etdadmin_upload_1012786
-
- Description:
- Pollution-intensive industrial manufacturing processes threaten the health of ecosystems and societies through toxic waste streams and energy intensive processes that lead to greenhouse gas emissions. Biological systems present more sustainable routes to many useful industrial chemicals by using enzymes at low temperatures, but the time and effort required to optimized...
- Keyword:
- Cell-free, Synthetic biology, Metabolic engineering, and Biomanufacturing
- Subject:
- Molecular biology and Chemical engineering
- Creator:
- Rasor, Blake
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_994770 and http://dissertations.umi.com/northwestern:16630
-
- Description:
- This dissertation focuses on quantifying protein folding stability determinants and presenting initial experiments that can guide the development of a novel assay that identifies cell-penetrating miniproteins. First, despite over a century of scholarship on protein folding stability, applying this knowledge to design proteins computationally remains limited. Usually, protein designers generate...
- Keyword:
- protein design, cell-penetrating protein, synthetic biology, and protein folding stability
- Subject:
- Biology, Cellular biology, and Biophysics
- Creator:
- Kim, Tae-Eun
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16695 and etdadmin_upload_1009800
-
- Description:
- Temperature affects all biological processes, from the rate of cellular growth and metabolism to the stability of proteins that make up the machinery of life itself. Thus, all organisms must have the capacity to detect and respond to external temperature. Thermosensation endows animals with the ability to sense and respond...
- Keyword:
- behavior, thermosensory, drosophila, and neural circuit
- Subject:
- Neurosciences
- Creator:
- Jouandet, Genevieve
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16434 and etdadmin_upload_965903
-
- Description:
- This dissertation presents novel advancements in the field of continuous nonlinear optimization, focusing on the development of efficient second-order methods for second-order conic programs (SOCPs) and continuous nonlinear two-stage optimization problems. The primary focus is on the theory and computations of Sequential Quadratic Programming (SQP) methods, which are widely used...
- Keyword:
- Nonlinear Optimization, Second-order Cone Programs, Two-stage Optimization, and Sequential Quadratic Programming
- Subject:
- Industrial engineering and Operations research
- Creator:
- Luo, Xinyi
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1013576 and http://dissertations.umi.com/northwestern:16752
-
- Description:
- Recent progress in semiconductor synthesis and photophysics has revealed a host of new materials with exciting properties for applications in optoelectronic devices such as sensors, photovoltaics, solid state lighting, and more. One of the most significant recent additions to the field is the class of hybrid and inorganic materials that...
- Subject:
- Physical chemistry, Chemistry, and Materials Science
- Creator:
- Cuthriell, Shelby A
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16650 and etdadmin_upload_1000360
-
- Description:
- Bacterial infections (BI) are a frequent, expensive, and life-threatening condition for critically ill patients. For patients with serious BI, minimizing the time between admission to the intensive care unit (ICU) and administration of appropriate antibiotic therapy is crucial to improve prognosis. However, the current gold-standard for identifying the appropriate antimicrobials...
- Keyword:
- MIMIC, Antibiotic Stewardship, Clinical Prediction, Critical Care, Machine Learning, and Electronic Health Records
- Subject:
- Icelandic & Scandinavian literature and Bioinformatics
- Creator:
- Eickelberg, Garrett
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_999752 and http://dissertations.umi.com/northwestern:16645
-
- Description:
- Herein, we present an overview of our studies of the morphology, dynamics, and formation of heterogeneous soft matter systems via the emerging technique of liquid phase transmission electron microscopy (LPTEM). This particular subset of materials, more commonly referred to as emulsions, is tremendously commercially and biologically relevant, encompassing applications in...
- Keyword:
- liquid phase transmission electron microscopy, soft matter, emulsions, polymers, and surfactants
- Subject:
- Polymer chemistry and Materials Science
- Creator:
- Vratsanos, Maria A.
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1009969 and http://dissertations.umi.com/northwestern:16698
-
- Description:
- This dissertation explores the entanglements of performed refusals and witnessing practices in the face of gendered violences. I analyze how contemporary artists use staged performance to generate new modes for witnessing histories of gendered violence across temporal and national boundaries. In particular, I investigate four performances addressing local histories of...
- Keyword:
- Redress, Transnational Feminisms, Refusal, Embodiment, Performance, and Gendered Violence
- Subject:
- African American studies, Gender studies, and Dance
- Creator:
- Ross, Danielle
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16764 and etdadmin_upload_1013748
-
- Description:
- Volunteers play an essential role in humanitarian and non-profit organizations that strive to improve society. 30% of the population in the United States volunteered in 2019, and this percentage has been stable for the past two decades. This dissertation is motivated by the scheduling decision process in nonprofit organizations. These...
- Keyword:
- volunteer scheduling and nonprofit operations
- Subject:
- Logic and Operations research
- Creator:
- Escallon-Barrios, Mariana
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16687 and etdadmin_upload_1009527