The overall goal of my thesis is to enhance our quantitative understanding of the biophysical properties of DNA a long polynucleotide chain, present in every living cell, that embodies the genetic information. The existence of DNA has been known to us for over a century, however, our understanding of its...
In the last decade, global mobile data traffic increased by more than a hundred fold times while maintaining essentially the same monthly charge to the average mobile user. Cisco predicts that overall mobile data traffic will continue to grow rapidly at a compound annual growth rate of 60 percent between...
Biology is entering the exciting world of big data. Modern high-throughput experimental techniques often produce large datasets that aim to capture complex relationships often found in biological systems. While these larger data sets contain vast amounts of useful information, the answers are often locked behind a wall of numbers. As...
In polymer nanocomposites (PNCs), the physical and chemical interactions at the polymer matrix-filler interface lead to local variations in polymer properties, creating a substantial interphaseregion in the vicinity of the interface. Quantifying the significance of the interphase effect in the presence of substrates or nanoparticles is of essential importance in...
The dissertation consists of three separate essays that lie at the interface of social network analytics and Customer Relationship Management (CRM). Essay 1 and Essay 2 cover completed research, while the research covered in Essay 3 is at a more preliminary stage.', 'Essay 1: Starting Cold: The Power of Social...
Many phenomena that occur in the nanoscale, such as the self-assembly of charged amphiphiles, the metal extraction for recovering rare earth elements and nuclear waste as well as water purification, are driven by the electrostatic forces. Although current simulation techniques can handle the long-range Coulomb potential efficiently, the inhomogeneity in...
Stringent demands in the sheet forming industry related to rapid and customized part realization coupled with rigorous requirements on geometric accuracy and product properties have outpaced the capabilities of traditional forming processes. As an emerging novel technology, Double-Sided Incremental Forming (DSIF) offers much higher flexibility with the complete elimination of...
Machine learning and symbolic reasoning have been two main approaches to build intelligent systems. Symbolic reasoning has been used in many applications by making use of expressive symbolic representations to encode prior knowledge, conduct complex reasoning and provide explanations. Recently, machine learning has enabled various successful applications by learning from...
Migrant illegality gives way to irregular livelihoods in Spain and around the world. Studies on migrant illegality have generally focused on its political, legal and economic production and the social impact of a states specific biopolitics. While invaluably important, there remains the need to better understand the modes of life...
Cultivating Citizens: Ecology and Nationality in U.S. Immigrant Literature explores how and why American ecosystems became objects of appreciation, intervention, and attachment within immigration literature published during the eighteenth- and nineteenth-century. Fictional and nonfictional stories about US-bound immigrants represented naturalization and nationality as materializing through interactions within human/nonhuman assemblageswhat we...
We tackle two important theoretical problems in macroeconomics and international economics. First, in macroeconomics, especially monetary economics, the models with a standard Taylor rule have multiple equilibria. This multiplicity is problematic since we do not have a theory to determine a price level. We propose a theory to pin down...
Visual Regression is a general task in the area of computer vision, with input visual data space and continuous output space. Most learning-based visual estimation tasks, where the output variables take values in continuous space, are related to visual regression. Examples of visual regression include many emerging but very difficult...
The rat whisker system has been a longstanding and fruitful model system for sensory neuroscience, because of its status as an œexpert active sensing system, and many open avenues of research still remain. One large-scale goal of the field is to œclose the loop from sensation to movement, modeling how...
Heterogeneous materials have been emerging and playing essential roles in various engineering and scientific fields. They usually include multiple phases of materials to create unique properties that are not accessible to their homogeneous counterparts. The traditional design approach in the material science community is to use trial-and-error iteratively, which is...
Recently, there has been increasing interest in exploring nano-materials used as an additive to existing concrete materials. With respect to fiber-shaped nanomaterials such as carbon nanofibers (CNF), many studies have shown that mechanical strength properties of cementitious materials can be improved significantly. In this dissertation, the research has focused on...
This dissertation is situated at the intersection of critical philosophy of race, affect theory, and new media studies. The dominant questions of my research consider what new problems and avenues of thought the digital age and social media open up for the study of race. This focus includes the ways...
Recently, much public attention has been focused on racial inequalities in who is subjected to exclusionary school disciplinary policies, and consequently, forced to miss hours of instruction. Over the past two decades, researchers have documented the disparate impacts that zero-tolerance policies have had on students of color, low-income students, and...
While scholarship over recent decades has complicated the traditional classification of the Bavlis texts into the field has still maintained a model of two separate, though fundamentally interrelated, discourses. According to this model, the Bavli consists of a normative, non-narrative, legal discourse alongside an antinomian, narrativized discourse of stories. Through...
Chip-based photonic devices are doing for optics what integrated circuits have done for electronics. By directly combining many individual components in a compact, scalable and robust way, photonic chips open the possibility for creating optical and electro-optical devices that could not be practical with discrete components. The applications for this...
Herpesvirus virions consist of three layers: nucleocapsid, tegument, and envelope. The innermost layer, the nucleocapsid, initially assembles as an immature procapsid precursor built around viral scaffold proteins. The event that initiates procapsid maturation is unknown but it is dependent upon activation of the internal protease. Scaffold cleavage triggers angularization, or...