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- Description:
- Microfluidic technologies enable multi-tissue culture and precise control of media exchange and therefore have significant potential to create more complex in vitro models of reproductive systems, including endocrine cycles. However, microfluidic technologies have largely been applied to gamete-level culture in reproductive biology, with very little progress in organ-level culture. Herein...
- Keyword:
- Toxicity, Oocyte, 3D Printing, Ovary, Microfluidics, and Islet
- Subject:
- Obstetrics, Biology, and Biomedical engineering
- Creator:
- Rogers, Hunter Bradley
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_661219 and http://dissertations.umi.com/northwestern:14603
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- Description:
- Pathogenic bacteria scavenge essential nutrients including metals, amino acids and peptides to survive within the hostile host environment. Bacteria utilize ATP-binding cassette (ABC) transporters, powered by the energy of ATP hydrolysis, to move substrates across cellular membranes. The substrate-binding protein (SBP) shuttles substrate in the periplasm and directs the substrate...
- Keyword:
- ABC transporters, substrates, peptides, binding proteins, and heme
- Subject:
- Biology and Biophysics
- Creator:
- Tanaka, Kari J
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14534 and etdadmin_upload_640137
-
- Description:
- A functional democratic society rests on the premise that the mass public holds clear preferences for policies, candidates, and more. To arrive at these preferences, many citizens rely on their social identities, making political decisions based on what they see as benefitting the groups to which they belong. They may...
- Subject:
- Social psychology and Political science
- Creator:
- Howat, Adam
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_682262 and http://dissertations.umi.com/northwestern:14780
-
- Description:
- In an 18-month ethnographic and interview-based study of Afghan Americans in the greater Bay Area, California, I explore the relationship of culture and religion amongst this refugee community. As a majority of refugees in the past decade have been Muslim, it is important to understand what their process of integration...
- Keyword:
- immigration, racialization, Islam, Afghan, identity, and Muslim
- Subject:
- Sociology, Religion, and Ethnic studies
- Creator:
- Ahmad-Sediqe, Iman
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_653428 and http://dissertations.umi.com/northwestern:14561
-
- Description:
- Methylation of histone 3 lysine 4 (H3K4) catalyzed by the COMPASS family of lysine methyltransferases is universally associated with eukaryotic transcription. However, despite thousands of published studies examining the deposition, dynamics, and genomic positions of this chromatin modification, there is no clear consensus as to the molecular function or biological...
- Subject:
- Biochemistry
- Creator:
- Rickels, Ryan A
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14787 and etdadmin_upload_682860
-
- Description:
- Oocyte meiosis is a specialized, but error prone, form of cell division that is poorly understood. Errors during meiosis often result in aneuploidy, or abnormal chromosome number, that impacts human health and fertility. Aneuploidy is the leading cause of miscarriages and birth defects, such as Down's syndrome in which cells...
- Keyword:
- chromosome segregation, spindle, meiosis, midzone, oocyte, and anaphase
- Subject:
- Molecular biology and Cellular biology
- Creator:
- Heath, Carissa Marie
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_663079 and http://dissertations.umi.com/northwestern:14678
-
- Description:
- Visual matching is an important and fruitful research topic in computer vision area. Starting from the early face recognition, super-resolution, object tracking to the most recent person re-identification, cross-model retrieval, visual matching plays an important role as the core component in these tasks. The quality of visual matching directly and...
- Keyword:
- person re-identifciation, small-size samples, visual matching, and metric learning
- Subject:
- Computer science
- Creator:
- ZHOU, JIAHUAN
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_625781 and http://dissertations.umi.com/northwestern:14443
-
- Description:
- Emotion perception is multisensory and involves decoding and integrating input from both visual and auditory modalities. This dissertation investigates the influence of cultural and linguistic experience on multisensory perception of emotion. Experiment 1 examines the effect of cultural background on modality bias (i.e., the amount of influence a modality exerts...
- Keyword:
- cultures, modality bias, multisensory integration, and emotion perception
- Subject:
- Cognitive psychology
- Creator:
- Chen, Peiyao
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14633 and etdadmin_upload_662275
-
- Description:
- The study of the translucent interstellar medium (ISM) is important for understanding the behavior of the ISM as it transitions from hot, tenuous gas to dense, star-forming regions. This regime is know to be associated with the initial formation of persistent molecular material, and thus represents the first stages of...
- Keyword:
- spectroscopy and ISM
- Subject:
- Astronomy and Astrophysics
- Creator:
- Dirks, Cody
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14726 and etdadmin_upload_670810
-
- Description:
- The rapid development of flexible electronics enables a huge amount of bio-integrated applications with advantages of the mechanical compliance, stretchability and comformability of the devices. My dissertation further advances this area by a series of projects, which include designing and optimizing novel compliant structures, proposing novel elastomer encapsulation process for...
- Keyword:
- Three-dimensional Assembly, Wearable electronics, Mechanical Design and Analysis, Stretchable and flexible electronics, Thermo-electric Energy Harvester, and Microflyer
- Subject:
- Electrical engineering, Mechanical engineering, and Fluid mechanics
- Creator:
- Li, Kan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_635054 and http://dissertations.umi.com/northwestern:14498
-
- Description:
- Successfully grappling with the widespread linguistic variation of daily life requires speakers to adapt to systematic variation in the environment while discarding incidental variation, based on their prior experience. In the case of phonotactics, speakers’ prior experience is that talkers who differ in their language background are likely to vary...
- Keyword:
- Phonotactics, Accent adaptation, Causal Inference, Adaptation, Adult language learning, and Phonotactic learning
- Subject:
- Linguistics
- Creator:
- Denby, Thomas
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14735 and etdadmin_upload_674207
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- Description:
- Wastewater and bioreactors in wastewater treatment plants (WWTPs) are reservoirs for antibiotic resistance genes (ARGs), which can pass through treatment processes and migrate into the environment as they are released in effluent. WWTPs harbor a variety of ARGs that can be spread by horizontal gene transfer facilitated by mobile genetic...
- Keyword:
- viruses, antibiotic resistance genes, biofilms, wastewater, and mobile genetic elements
- Subject:
- Microbiology, Environmental engineering, and Bioinformatics
- Creator:
- Petrovich, Morgan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_671878 and http://dissertations.umi.com/northwestern:14727
-
- Description:
- Store-operated Ca2+ entry through Orai1 channels mediate transcriptional, proliferative, and effector cell programs in many cells and are activated through a unique inside-out mechanism involving binding of the endoplasmic reticulum Ca2+ sensor, STIM1, to cytoplasmic sites on Orai1. Mutations in Orai1 that block channel activation or evoke constitutive channel activity...
- Keyword:
- Orai1, Gating, STIM1, Channel, CRAC, and Calcium
- Subject:
- Pharmacology, Biology, and Biophysics
- Creator:
- Yeung, Priscilla See-Wai
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_622219 and http://dissertations.umi.com/northwestern:14422
-
- Description:
- This dissertation explores hip-hop as a moral philosophy in action; a set of aesthetic and ethical values that manifest in young people’s perspective about the good life. Hip-hop is an arts movement of rap, movement, and style originating among Black and Latinx youth in the South Bronx during the late...
- Keyword:
- moral pluralism, hip-hop culture, cultural psychology, value socialization, and morality
- Subject:
- Education
- Creator:
- Nzinga, Kalonji
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_633203 and http://dissertations.umi.com/northwestern:14488
-
- Description:
- Numerous photophysical processes in both natural and artificial systems are dictated by the interaction between chromophores. For example, in photosynthesis, light is absorbed by an antenna complex composed of an array of chlorophyll chromophores that collectively transfer the energy to the reaction center where interactions between a series of redox...
- Keyword:
- Time-resolved spectroscopy, Electron transfer, Photophysics, Quantum coherence, Singlet fission, and Excimer
- Subject:
- Physical chemistry
- Creator:
- Phelan, Brian Thomas
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_633520 and http://dissertations.umi.com/northwestern:14489
-
- Description:
- Social comparison is a ubiquitous part of social life. People compare themselves to others to establish and maintain a sense of social hierarchy and structure, to develop and sustain interpersonal relationships, and even to help understand themselves. In this dissertation, I focus on how the referent of social comparison –...
- Keyword:
- Identity, Similarity, Social Comparison, Relationships, Innovation, and Metacognition
- Subject:
- Social psychology and Experimental psychology
- Creator:
- Galoni, Chelsea
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14559 and etdadmin_upload_652709
-
- Description:
- The critical importance of alternative mRNA splicing and the RNA binding proteins that orchestrate this essential layer of post-transcriptional gene regulation is increasingly recognized in gene regulatory programs. We and others have shown that alternative splicing plays a causal role during the Epithelial-Mesenchymal transition, a cell-developmental program that is hijacked...
- Keyword:
- splicing factor, RNA, EMT, alternative splicing, RNA binding protein, and metastasis
- Subject:
- Bioinformatics and Biology
- Creator:
- Harvey, Samuel
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14663 and etdadmin_upload_662828
-
- Description:
- Viral Verses investigates the influence of social media publication on the relationship between poetry and community formation in southeastern Africa. As more artists in the global South reach wider audiences through online publication, poetic form has shifted to reflect social media’s aesthetic norms, embracing urgency, contemporaneity, and populism. Digital media...
- Keyword:
- Aesthetic networks, Southeastern Africa, Literary history, Social media, Poetry and poetics, and Poetry performance
- Subject:
- Sociology, Literature, and African literature
- Creator:
- Sacks, Susanna L
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_666603 and http://dissertations.umi.com/northwestern:14695
-
- Description:
- Increasing industrialization and the resulting negative environmental impacts highlight the need to develop alternative renewable energy sources. The Sun is a massive source and organic solar cells are a growing field of study. As new materials are synthesized, the efficiencies of organic solar cells continue to grow, but without an...
- Keyword:
- x-ray scattering, transient absorption, and organic solar cell
- Subject:
- Physical chemistry, Chemistry, and Materials Science
- Creator:
- Lou, Sylvia Jen-Ming
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_626768 and http://dissertations.umi.com/northwestern:14458
-
- Description:
- Surface-enhanced Raman spectroscopy (SERS) is a powerful analytical technique that can detect single molecules and simultaneously obtain structural information. When an analyte molecule binds to a nanostructured noble metal surface, the otherwise weak normal Raman signal is enhanced by as much as a factor of 108. This makes SERS the...
- Keyword:
- Surface-Enhanced Raman Spectroscopy and single molecule spectroscopy
- Subject:
- Physical chemistry and Nanoscience
- Creator:
- Wong, Nolan Log-chi
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14406 and etdadmin_upload_617842