Traditional bottom-up mass spectrometry-based proteomics relies on the use of an enzyme, often trypsin, to generate small peptides (typically < 25 amino acids long). In top-down proteomics, proteins remain intact and are directly measured within the mass spectrometer. This technique, while inherently simpler than bottom-up proteomics, generates data which must...
Slides for a workshop for Northwestern University on sharing and preserving research findings using the library's resources. This workshop was delivered at Computational Research Day 2017.
This study explores the relationship between reading habits and reading materials, and academic success of primary school students in the Ontulili community of Kenya. The study revealed high levels of satisfaction and contentment among the participants with respect to the availability of resources, reading abilities, educational performance, and overall preparedness...
The genetic variants underlying complex traits are often elusive even in powerful model organisms such as Caenorhabditis elegans with controlled genetic backgrounds and environmental conditions. Two major contributing factors are: (1) the lack of statistical power from measuring the phenotypes of small numbers of individuals, and (2) the use of...
Publications from Northwestern University's Infrastructure Technology Institute. "The Theme Of The Infrastructure Technology Institute Is To Develop Strategies And Tools To Protect And Improve The Condition, Capacity, And Performance Of The Nation’s Highway, Railroad, And Mass Transit Infrastructure Systems." The Infrastructure Technology Institute (ITI) developed advanced methods for monitoring infrastructure...
Metabolic syndrome has become a major public health challenge worldwide. The association between metabolic syndrome and DNA methylation is of great research interest. We constructed a binomial model to investigate the association between a metabolic syndrome index and DNA methylation in the Normative Aging Study. We applied the Iterative Sure...
The Affordable Care Act (ACA) has expanded health coverage for thousands of Illinois residents. Expanded coverage, however, does not guarantee appropriate health care. Diabetes and its ocular complications serve as an example of how providers in underserved urban areas may not be able to keep up with new demand for...
State borders allocate access to basic goods, opportunities, rights, and protections along lines of nationality, race, and gender. However, the discriminatory effects of state borders rarely appear as an issue in the self-understanding of liberal-democratic societies and their political theorizing. In this paper, I explore how the category of nationality...