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  1. The Modulation of Magnetic Properties In Magnetic Resonance Imaging Contrast Agents using Enzymes

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    Description: Magnetic resonance imaging (MRI) is an advanced imaging modality that is experiencing increasing popularity in clinical and experimental settings. MRI enjoys the benefit of high-resolution, the use of non-ionizing radiation, and the ability to distinguish between soft tissues. MR imaging is enhanced with the use of Gd3+ chelated contrast agents;...
    Keyword: Chemistry
    Subject: Chemistry
    Creator: Paul J Lee
    Owner: Scholarly Digital Publishing
    Date Uploaded: 09/17/2018
    Date Modified: 09/17/2018
    Date Created: 2008-10-30
    Rights: In Copyright
  2. System-Level Synthesis and Verification

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    Description: As device sizes decrease, more functionality can be placed in an integrated circuit. Therefore, the design complexity of these circuits increases. To deal with complexity, designers move to higher abstraction levels. Currently, the highest abstraction level is the system-level. In our work we investigate the synthesis and verification problem at...
    Keyword: Engineering and Computer Science
    Subject: Electrical and Computer Engineering
    Creator: Nikolaos Liveris
    Owner: Scholarly Digital Publishing
    Date Uploaded: 09/17/2018
    Date Modified: 09/17/2018
    Date Created: 2008-10-02
    Rights: In Copyright
    Resource Type: Dissertation
  3. Do Stock Mergers Create Value for Acquires?

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    Description: This dissertation studies whether stock mergers creates value for acquirers. The first chapter of this dissertation conducts a comprehensive review of the existing merger literature relevant to this topic. It includes existing merger theories, empirical studies on whether mergers are value destroying or value creating, and methodological issues on empirical...
    Keyword: Finance and Economics
    Subject: Finance
    Creator: Qi Lu
    Owner: Scholarly Digital Publishing
    Date Uploaded: 09/17/2018
    Date Modified: 09/17/2018
    Date Created: 2008-10-02
    Rights: In Copyright
    Resource Type: Dissertation
  4. Mechanistic Modeling of Polymer Pyrolysis: Investigation of Intrinsic Kinetics, Reaction Pathways, and Structural Heterogeneities

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    Description: Resource recovery is a promising category of polymer recycling where polymeric waste is converted via thermal or chemical means to monomer and chemical feedstocks. Specifically, pyrolysis is an attractive method because of its simplicity and ability to handle a heterogeneous feedstock. Polymer pyrolysis is characterized by a complex free radical...
    Keyword: Chemical Engineering
    Subject: Chemical and Biological Engineering
    Creator: Seth Elon Levine
    Owner: Scholarly Digital Publishing
    Date Uploaded: 09/17/2018
    Date Modified: 09/17/2018
    Date Created: 2008-08-29
    Rights: In Copyright
    Resource Type: Dissertation
  5. Design and Production of Protein-Based Polymers for Application as Drag-Tags in Free-Solution DNA Sequencing

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    Description: End-Labeled Free-Solution Electrophoresis, or ELFSE, is an alternative strategy for DNA sequencing that proposes to eliminate the need for a viscous sieving matrix for size-based DNA separation. In this bioconjugate method, a perturbing entity or "drag-tag" is attached to differently sized DNA fragments produced by the Sanger reaction. This drag-tag...
    Keyword: End-labeled free-solution electrophoresis, DNA sequencing, protein polymer, and bioconjugation
    Subject: Chemical and Biological Engineering
    Creator: Jennifer Lin
    Owner: Scholarly Digital Publishing
    Date Uploaded: 09/17/2018
    Date Modified: 09/17/2018
    Date Created: 2008-08-20
    Rights: In Copyright
    Resource Type: Dissertation
  6. Biofilm Modeling for Wastewater Treatment: Multiple Species and Multiple Components

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    Description: This work explores the development and implementation of a biofilm model for multiple solid species and multiple dissolved components. The model makes use of several different advanced numerical methods in order to achieve the goal of describing the behavior of biofilms growing in wastewater treatment reactors. Using the model we...
    Keyword: EPS, soluble microbial products, multi-species, multi-component, and biofilm
    Subject: Applied Mathematics
    Creator: Brian Vernon Merkey
    Owner: Scholarly Digital Publishing
    Date Uploaded: 09/17/2018
    Date Modified: 09/17/2018
    Date Created: 2008-08-04
    Rights: In Copyright
    Resource Type: Dissertation
  7. Mechanism of Nuclear Import of a Smooth Muscle Cell-Specific Plasmid Vector for Gene Therapy

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    Description: Cardiovascular disease is a leading cause of morbidity and mortality worldwide. While many therapies have been used to treat vascular disease symptomatically, gene therapy offers a means of treating the molecular dysfunctions driving disease pathogenesis. Unfortunately, gene therapy has achieved only modest therapeutic success in clinical trials due to a...
    Keyword: nuclear localization signal, plasmid, nuclear import, karyopherins, and gene therapy
    Subject: Integrated Graduate Program in the Life Sciences
    Creator: Aaron Michael Miller
    Owner: Scholarly Digital Publishing
    Date Uploaded: 09/17/2018
    Date Modified: 09/17/2018
    Date Created: 2008-08-01
    Rights: In Copyright
    Resource Type: Dissertation
  8. Structural and Functional Analyses of Herpes Simplex Virus Type1 Glycoproteins B and L, Two Essential Components of the Viral Fusogenic Complex

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    Description: Herpes simplex virus (HSV) infection of host cells requires virus attachment to the cell surface and subsequent membrane fusion between the virus envelope and host cell membrane to deliver the nucleocapsid containing the viral genome into the host cell. A proposed mechanism for HSV glycoprotein-induced membrane fusion is gD binding...
    Keyword: Biology
    Subject: Integrated Graduate Program in the Life Sciences
    Creator: Erick Lin
    Owner: Scholarly Digital Publishing
    Date Uploaded: 09/17/2018
    Date Modified: 09/17/2018
    Date Created: 2008-07-17
    Rights: In Copyright
    Resource Type: Dissertation
  9. Charge Dynamics in New Architectures for Dye-Sensitized Solar Cells

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    Description: The promise of a clean, renewable, and abundant energy supply make the efficient conversion of solar energy to electricity a compelling scientific and societal goal. In the following chapters, I will describe my efforts to advance one class of photovoltaic technology, dye-sensitized solar cells, by demonstration and characterization of unexplored...
    Keyword: Architectures, Energy, Dynamics, Solar, Dye-Sensitized, and Photovoltaic
    Subject: Chemistry
    Creator: Alex Martinson
    Owner: Scholarly Digital Publishing
    Date Uploaded: 09/17/2018
    Date Modified: 09/17/2018
    Date Created: 2008-06-11
    Rights: In Copyright
    Resource Type: Dissertation
  10. Effects of chitosan on the alignment, morphology and shape of calcite crystals nucleating under Langmuir monolayers

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    Description: The mechanisms governing selective CaCO3 crystal nucleation in living organisms remain unclear. For example, nacreous layers from the inner surfaces of shells are built as brick-and-mortar complexes of plate-like aragonite single crystals and organic layers. Unstable [001] surfaces of calcite columns in prismatic layers are also stabilized by organic molecules....
    Keyword: SEM, Chitosan, Calcite, Grazing incidence x-ray diffraction, Biomineralization, and Langmuir monolayer
    Subject: Physics and Astronomy
    Creator: Kyungil Kim
    Owner: Scholarly Digital Publishing
    Date Uploaded: 09/17/2018
    Date Modified: 09/17/2018
    Date Created: 2008-11-21
    Rights: In Copyright
    Resource Type: Dissertation