This thesis contributes in two ways. First it describes a new framework for the systematic design of collective behaviors and solves a key stability issue under this design framework. In this thesis we apply this framework to solve three tasks in the swarm robotics field: connectivity maintenance, formation control and...
Sufficient vocal fold superficial hydration is indispensable to maintain normal vocal function and protect vocal fold epithelium against invasion of pathogenic agents. Vocal fold surface hydration is probably regulated by its electrophysiological properties. We hypothesized that the tight junction (TJ)-related paracellular barrier contributes to the maintenance of those properties. Therefore,...
Solder joint integrity is recognized as a key issue in the reliability of flip chip and ball grid arrays in integrated circuit packages. Significant reductions in the solder-joint interconnect size results in both the increased volume fraction of brittle intermetallics in the joint and joule heating and electromigration failure due...
T-cell activation is an essential step of the immune response, yet the cellular and molecular events underlying this complex process are not fully understood. Significantly, a comparative genome-scale transcriptional analysis of two T-cell subsets and the natural-mixed CD3+ population remains unexplored. Using microarrays, we investigated the temporal global transcriptional profile...
The studies in this thesis are directed towards defining the signaling mechanisms that regulate astrogliosis after SCI and towards developing potential therapeutic techniques for modifying this process. The central hypothesis is that alteration of the extracellular milieu after SCI can limit the deleterious effects of glial scar formation and enhance...
The light field is a 4D function that describes the flow of light in all directions through every point in free space. Digital cameras only capture a 2D projection of the 4D light field entering the camera lens. In this dissertation I modify the light field as it enters a...
I examine how consumers' purchase' decisions and intentions of purchases are affected by uncertainty about future deals (temporary price cuts or sales) for a product and how these results affect retailers' optimal pricing and marketing strategies. First I look at the effects of uncertainty about the timing of deals (i.e....
The mechanisms governing selective CaCO3 crystal nucleation in living organisms remain unclear. For example, nacreous layers from the inner surfaces of shells are built as brick-and-mortar complexes of plate-like aragonite single crystals and organic layers. Unstable [001] surfaces of calcite columns in prismatic layers are also stabilized by organic molecules....
In the first chapter we analyze profits and efficiency implications of a relation between an upstream duopoly and downstream monopoly in Hotelling linear city model. While exclusive contracts maximize the monopolist's profit, at the same time socially they are inefficient. Linear prices, while more efficient, usually also do not achieve...
Chagas heart disease, caused by infection with the protozoan parasite Trypanosoma cruzi, is still regarded as a major public health problem in Central and South America. The finding of cardiac specific autoimmunity during infection in both humans and experimental animals has provided a basis for investigation of its potential role...