Preparation and Characterization of Assembled Nanostructures by Peptide AmphiphilesPublic Deposited
The aim of this research is to investigate the pH effect on the assembled nanostructures of peptide amphiphiles (PAs). Controlling the sizes and shapes of these assembled nanostructures is of great importance for their ultimate applications in drug delivery, tissue engineering, and regenerative medicine. A complete characterization of these nanostructures can lead to further knowledge of how to control their structural features by manipulating their assembly environment. In this work the nanostructures were imaged and analyzed by atomic force microscopy (AFM) operating at tapping mode. AFM imaging results show a consistent effect of pH on the samples’ height and width. A consistent change of assembled nanostructures was observed with variation in NaOH concentration.