Eukaryotic genomes are organized into chromatin, which acts to regulate access to the organism’s genetic material. A large and diverse class of proteins, known as chromatin modifiers and remodelers, are responsible for regulating the composition and structure of chromatin by monitoring nucleosomes. Chromatin remodelers are involved in multiple cellular processes,...
The rise and racial gap in maternal mortality and morbidity in the US growing public health crisis. The US maternal mortality rate is double that of peer countries such as the UK and Canada. Even more striking, Black women are 243% more likely to die from childbirth-related causes. According to...
I present concepts and methods for evaluating infrared camera systems. The individual components of camera systems are fairly well understood, but the system is more than the sum of its parts. Many of the usual techniques for measuring individual photodetectors are inapplicable to pixels which are permanently bonded to a...
The ability to control the crystalline ordering and morphology of polymeric nanomaterials is a grand challenge in the field of materials science, which could enable the development of functional materials able to solve long-standing problems in renewable energy and medicine. In this work, we explore a combination of supramolecular chemistry...
This dissertation examines how theatre makers, activists, and politicians staged performances as a tool for rebuilding Catalan cultural identity and strengthening the Catalan independence movement. Through these performances, many Catalonians have sought to define their identity by invoking a retrospective of abuse and trauma, while presenting a united—albeit simplified and...
X-rays have become a staple in the investigation of the natural world. The high penetration and short wavelength of X rays means extended samples can be imaged at high resolution. With the increasing brightness of synchrotron light sources as well as the development of commercial sources the continued development and...
Finite Element Method (FEM) is a common simulation method in Computer Aided Engineering (CAE) or studying natural phenomenon by numerically solving Partial Differential Equations (PDEs). Programmable solvers for generic physics and geometry are thus highly desirable. However, the classical solvers are mostly complex systems in terms of both their mathematical...
Biomedical imaging is an essential part of medicine that enables the non-invasive observation of biological phenomena. This, in turn, allows for more accurate and earlier diagnoses, monitoring of therapies, and even fundamental research into biological processes. Molecular imaging, a fast-growing subdiscipline of biomedical imaging, seeks to image biochemical processes at...
Individuals with psychotic disorders experience profound challenges in maintaining a coherent sense of self and identity over time. Although disturbances in the basic, momentary sense of self are core features of psychotic experiences, less is known about psychosis’s impact on the autobiographical self, the experience of being a coherent and...
This dissertation explores the experience of violence and precarity among Central American youth as they travel through Mexico to the United States. Based on a multi-sited ethnographic study conducted across Mexico from 2015 to 2019, I illustrate how the journey of these youth migrants is, in its basic expression, an...