Various methods for solving the partial contact of surfaces with regularly periodic profiles-- which might arise in analyses of asperity level contact, serrated surfaces or even curved structures--have previously been employed for elastic materials. A new approach based upon the summation of evenly spaced Flamant's solution is presented here to...
This dissertation concerns the rhetorical discourses that define a wireless technology revolution in the United States. This inquiry engaged in rhetorical criticism of key documents, texts and exigencies embedded within successive stages of the wireless revolution spanning twenty years. Three sites of discourse were analyzed: the wireless industry's vision and...
Using a novel DNA-microarray hybridization protocol, the diffusion distance during static microarray hybridization was estimated for Cy3- and Cy5-labeled cDNA probes as 3.8 and 2.6 mm, respectively, despite having almost identical molecular masses. Continuous mixing during microarray hybridization resulted in a 15-20% increase in signal intensity over arrays hybridized statically....
Two new methods have been developed employing silicon-containing molecules in novel organic transformations. The first strategy utilizes Lewis base-activation of triethoxysilylalkynes to deliver mild acetylide nucleophile equivalents. The second approach involves the use of enolate additions to acylsilanes to generate β-silyloxy homoenolate intermediates.
Lewis base-catalyzed activation of triethoxysilylalkynes promotes the...
In a highly competitive market, it is becoming increasingly important to view product design as an enterprise-level profit-driven activity. Demand models have become central to enterprise-driven design approaches since they help estimating the economic impact (e.g., revenues, profits, and cost) of a product's design. The primary contribution of this dissertation...
This dissertation examines the history of Mexicans' changing racial status in the Chicago metropolitan region, a place where race has traditionally been understood in strictly black and white terms. From World War I through the 1930's whites violently resisted Mexicans moving into their neighborhoods in Chicago, East Chicago, and Gary,...
This dissertation focuses on the utilization of two coordination chemistry-based synthetic approaches, which provide the ability to rapidly and quantitatively assemble sophisticated supramolecular cofacial porphyrin complexes. Significantly, by adopting a coordination chemistry-based approach, the porphyrin-porphyrin interactions can be regulated in situ via the addition or removal of chemical effector molecules....
Aluminum alloys strengthened with coherent (L1<sub>2</sub>), nanosize Al<sub>3</sub>Sc precipitates may be used as structural materials at elevated temperatures. They are creep resistant at 300°C and exhibit a threshold stress, below which creep is not measurable. Introducing ternary alloying additions, such as rare-earth elements (RE=Y, Dy, Er), that segregate within Al<sub>3</sub>Sc...
HspB2 was discovered as a chaperone of muscular dystrophy protein kinase (DMPK) and originally named, DMPK binding protein (MKBP) and presently called HspB2. Functionally, MKBP binds to DMPK and stabilizes its kinase activity, thereby accelerating the progression of muscular dystrophy. Although other binding partners of HspB2 have been found, the...
A series of investigations was undertaken to explore the processing and properties of porous titanium with 6 wt% Al and 4 wt% vanadium (Ti-6Al-4V) and an equiatomic nickel-titanium alloy (NiTi). In this study, porous materials were created in the solid state by entrapping argon in a powder compact, and subsequently...