Solid oxide fuel and electrolysis cells (SOFCs and SOECs) must be engineered with the entire lifetime of their performance in mind. Electrochemical activity will decrease as degradative processes take effect, leading to higher overpotentials and decreased power outputs. Materials science and engineering can stave off these inefficiencies through an understanding...
Failed continental rifts provide unique opportunities to study aspects of plate tectonic evolution frozen in time. North America contains three major failed rifts: The Midcontinent Rift (MCR), Southern Oklahoma Aulacogen (SOA), and the Reelfoot Rift (RR). To understand why some rifts fail and why others might succeed to seafloor spreading,...
Heat shock factor 1 (HSF1) is well known for its role in the heat shock response (HSR), where it drives a transcriptional program comprising heat shock protein (HSP) genes, and in tumorigenesis, where it drives a program comprising HSPs and many noncanonical target genes that support malignancy. Here, we find...
Additive manufacturing (AM), also known as three-dimensional (3D) printing, has received considerable interests in recent years. It enables fabrication of complex, customizable parts that would otherwise be too expensive or impossible for traditional manufacturing methods. 3D printing encompasses a wide variety of processes, including photopolymerization, material extrusion, selective laser sintering,...
Digital behavior change interventions (e.g., mHealth, websites, behavior change apps) can be an effective way to engage groups who experience disadvantages in terms of social and economic attainment, with tailored health content and have potential to improve health outcomes and reduce health disparities. Given the importance and pervasiveness of behavior...
Chapter 1. Undergraduate Gender Diversity and Direction of Scientific Research (with Ashley Wong) Can diversity lead to greater research focus on populations underrepresented in science? Diverse researchers can bring new questions and perspectives, but exposure to diversity may also inspire scientists, regardless of demographic identity, to pursue new topics. This...
MYC regulates multiple gene programs, raising questions about the potential selectivity and downstream transcriptional consequences of MYC inhibitors as cancer therapeutics. MYC func-tions to either globally amplify RNA production or selectively regulates genes by repression or ac-tivation. In models of MYC inhibition by small molecules the functionality of MYC is...
Oil paintings are complex works of art, even on the molecular level. Drying oils cure into a solid film through autoxidation and polymerization reactions and then degrade, leading to changes in material properties and film stability. This chemistry can be captured in a computational model and used by researchers in...
Infection with the novel coronavirus, SARS-CoV-2, results in pneumonia and other respiratory symptoms as well as pathologies at diverse anatomical sites. An outstanding question is whether these diverse pathologies are due to replication of the virus in these anatomical compartments and how and when the virus reaches those sites. To...
With the rapid growth of demand for data center services, the energy and water use of data centers has become a critical concern in the contexts of energy use, climate change, and freshwater conservation. Therefore, understanding, quantifying, and optimizing the use of energy and water resources in data centers has...