Importance: Despite its efficacy, low tidal volume ventilation (LTVV) remains severely underutilized for patients with acute respiratory distress syndrome (ARDS). Physician under-recognition of ARDS is a significant barrier to LTVV use. We propose a computational method that addresses some of the limitations of the current approaches to automated measurement of...
In this work, we will focus on the “at the same time” or direct transcription approach which allow a simultaneous
method for the dynamic optimization problem. In particular, we formulate the dynamic optimization model with
orthogonal collocation methods. These methods can also be regarded as a special class of implicit...