Over the course of disease progression, half of adults with type II diabetes also develop diabetic peripheral neuropathy (DPN), peripheral nerve damage precipitated by the downstream metabolic effects of hyperglycemia, insulin resistance, and dyslipidemia. This multifactorial pathogenesis of DPN leads to various structural and physiological changes within the nerve, ultimately...
Perturbations to the physiology or impairments in the formation of synapses within the cochlea, specifically the ribbon synapses, result in decreased sensitivity to auditory stimuli. In example, prolonged exposure to moderately intense auditory stimuli, like power tools, can result in the swelling of nerve terminals, retraction of the postsynaptic membrane,...
Originally motivated by the emergence of networked systems lacking central coordination such as multiprocessors, wireless sensor networks and smart grids, the study of distributed optimization algorithms has been an active field of research spanning multiple decades. More recently, the rapid growth in the availability of high-dimensional datasets has posed the...
“Where Do We Come From? What Are We? Where Are We Going?” is the name for one of French artist Paul Gauguin’s most influential paintings. Unsurprisingly, these very questions have occupied the minds of countless philosophers, artists, and scholars since the beginning of human civilization. These questions become especially salient...
This dissertation is a case study of one midwestern city and its Latinx inhabitants. It explores the intertwined pursuit by ethnic Mexicans and Puerto Ricans of inclusion in union and electoral politics. The world of machine politics offered ethnic Mexicans and Puerto Ricans an avenue for inclusion. Central to this...
X-ray imaging at nano and micro-scale is of great importance for the material science and defense industry. Large penetration depth and low wavelength of x-rays offer an important potential to image objects at high resolution and in a non-invasive process. While the ever-growing community is pursuing novel applications and looking...
Existing scholarship documents the low levels of political power held by the American poor, and concomitant economic elite domination of Congress. Since the poor seldom elect lawmakers that share their descriptive traits, they necessarily rely on non-poor lawmakers virtually representing their interests. A key part of this virtual representation is...
Stress, trauma exposure, and posttraumatic stress disorder (PTSD) are associated with chronic health conditions. In the U.S., women of color face trauma at up to four times the national rate. They also contend with chronic stress from the intersectional hardships of racism, discrimination, sexism, and economic hardship that is the...
Individuals experience a wide variety of emotions in their everyday lives. Some experience more variety, or complexity, than others, called emotional complexity. There is a body of research that suggests that emotional complexity is beneficial for mental and physical health; yet more recent work has called these associations into...
My dissertation defends a hermeneutic conception of ideology and its critique that situates both in the world-disclosing function of language.I argue that we must conceive of ideologies as world-disclosing embodied interpretive schemas insofar as they guide our cognitive, affective, and conative access to reality by providing the background knowledge, meanings,...