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- Description:
- Meiosis is a highly regulated process necessary for proper chromosome division. Zincfluxes regulate mammalian meiosis; between prophase I and metaphase II, total intracellular zinc increases by 50%, while 20% of zinc is released in “zinc sparks” following fertilization. Although zinc fluxes had been shown to be conserved in mammals, it...
- Keyword:
- Xenopus, Sample Fixation, Zinc, Manganese, Fertilization, and EMI2
- Subject:
- Inorganic chemistry, Biology, and Biochemistry
- Creator:
- Seeler, John Frederick
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_819316 and http://dissertations.umi.com/northwestern:15573
-
- Description:
- Found in 1-2% of the population, bicuspid aortic valve (BAV) is the most common congenital cardiovascular disease and is associated with increased risk of aortic valve dysfunction and aortic disease. Current treatment is focused on surgical intervention either after the development of symptomatic aortic stenosis/regurgitation or aortic diameter thresholds. However,...
- Keyword:
- 4D flow, MRI, and Aorta
- Subject:
- Biomedical engineering and Medical imaging
- Creator:
- Scott, Michael Baran
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_817047 and http://dissertations.umi.com/northwestern:15540
-
- Description:
- While metabolic engineering can enable the sustainable bioproduction of new materials, efforts are often impeded by pathway bottlenecks. To mitigate the effects of toxic or reactive intermediates and resource competition resulting from heterologous pathway incorporation, bacterial microcompartments (MCPs) have recently been considered for engineered compartmentalization in bacterial host organisms. MCPs...
- Keyword:
- Tag Engineering, Metabolic Engineering, Cargo Encapsulation, Bacterial Microcompartments, and Genomic Integration
- Subject:
- Bioengineering and Chemical engineering
- Creator:
- Nichols, Taylor Marie
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_802174 and http://dissertations.umi.com/northwestern:15500
-
- Description:
- Understanding associative memory is fundamental for a variety of neurological and neurodegenerative diseases, however, a large proportion of this research has excluded female subjects due to unsubstantiated bias. By including intact females, ovariectomized females and males in the study of associative memory, clear sex differences in acquisition emerged. Female mice...
- Subject:
- Neurosciences
- Creator:
- Rapp, Amy
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_802347 and http://dissertations.umi.com/northwestern:15501
-
- Description:
- Concentrating on the work of Paul Celan and Yoko Tawada, my dissertation explores the complicated role played by plants in post-war and contemporary German-language literature. Reflecting on and engaging with the intricate dynamics of vegetative life without the prejudice that it simply stands for an inferior form of life to...
- Keyword:
- Migrant Literature, Paul Celan, Plants and Poetics, Tawada Yoko, and Theory of Language
- Subject:
- Comparative literature, German literature, and Literature
- Creator:
- Cao, Jan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15517 and etdadmin_upload_812913
-
- Description:
- Robot dynamics are typically highly nonlinear and their control is a challenging research topic without a single overarching algorithm that demonstrates the best performance. In this thesis, I derive a nonlinear control algorithm that uses an analytical, closed-form solution to compute feedback with controllability-based guarantees for convergence. The proposed algorithm,...
- Keyword:
- Obstacle avoidance, Koopman operators, Data-driven control, Controllability-based control, Sequential action control, and Stability
- Subject:
- Robotics
- Creator:
- Mamakoukas, Giorgos
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_819790 and http://dissertations.umi.com/northwestern:15586
-
- Description:
- The crystal structure of chalcogenides can vary from simple, ubiquitous structures of rock salt and zinc blende to unique structure types from the intricate packing of complex anionic building blocks. Exploratory synthesis and structural studies of novel chalcogenides containing these complex anions will augment the understanding of bonding in chalcogenides....
- Keyword:
- neutron detectors, synthesis science, chalcoborates, chalcophosphates, framework materials, and 2D materials
- Subject:
- Materials Science
- Creator:
- Chica, Daniel George
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15563 and etdadmin_upload_818510
-
- Description:
- This thesis consists of three chapters on macroeconomics with heterogeneous households. In the first chapter, I document that spousal labor supply substantially mitigates the impact of cyclical labor income risk on married households. Motivated by this evidence, I present a macroeconomic model with incomplete markets in which households are heterogeneous...
- Keyword:
- labor market, general equilibrium, and heterogeneous agents
- Subject:
- Economics
- Creator:
- Bardoczy, Bence
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_818634 and http://dissertations.umi.com/northwestern:15564
-
- Description:
- In this dissertation, I explore topics related to migration studies, with a focus on Chinese migration, as China has a long history of both domestic and international migration, with China having the third largest diaspora in the world. In the first chapter, I discuss how a lack of stable domestic...
- Subject:
- Labor economics
- Creator:
- Long, Joe Jiuyi
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_815406 and http://dissertations.umi.com/northwestern:15528
-
- Description:
- The opposing activities of phosphatases and kinases determine the phosphorylation status of proteins, yet kinases have received disproportionate attention in studies of cellular processes, with the roles of phosphatases remaining less understood. This dissertation describes the use of self-assembled monolayer laser desorption/ionization mass spectrometry (SAMDI-MS) together with peptide arrays to...
- Keyword:
- SAMDI-MS, Phosphatases, High-Throughput Experiments, Enzyme Specificity, β-Catenin, and Peptide Arrays
- Subject:
- Chemistry, Biochemistry, and Cellular biology
- Creator:
- Huang, Che-Fan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_819016 and http://dissertations.umi.com/northwestern:15570