PRC is a PGC-1 coactivator family member responsive to serum growth factors and up regulated in proliferating cells. Unlike PGC-1α and PGC-1β, PRC has not been studied extensively and and its function or regulation remains largely unknown. Both PGC-1α and PGC-1β have been shown to be important regulators of mitochondrial...
Previous research has shown that creative insight problem-solving is distinct from systematic analytical problem-solving. Behaviorally, a positive mood has shown to facilitate insights but without knowing the processes that are fundamental to insight, the mechanisms as to how a positive mood facilitates insights have remained unspecified. Here, we investigate the...
This thesis discusses the synthesis, self-assembly, and conductivity properties of novel oligothiophene derivatives with an emphasis on how molecular structure effects the assembly. In order to facilitate self-assembly in conjugated molecules, specific non-covenant forces were included into the molecular design of several derivatives. First, an amphiphilic oligothiophene derivative consisting of...
The work described in this dissertation focuses on the development of a general approach to create nanoscale transition metal chalcogenide materials and new methods for controlling architecture of gold pyramidal structures. In the former, we used chemical nanofabrication, a combination of top-down patterning and bottom-up solid-state synthesis, to achieve control...
Predictive modeling has emerged as a new research subject that studies a broad range of modeling techniques to provide confident prediction of the phenomenon of interest by integrating scientific principles together with both computer models and observed physical experiments. Motivated by overcoming the existing challenges, the objective in this dissertation...
Why do the institutional outcomes of armed separatist conflicts vary? Separatist conflicts have diverse institutional effects. Though many separatists hope to create sovereign states, few achieve their aims. More often, their conflicts lead to forms of intra-state autonomy, independent but unrecognized de facto states, or territories under foreign occupation. These...
<span style="font-family: Calibri;">BaNa-Y is a catalyst for reduction of nitrogen oxides (NO and NO<sub>2</sub>) with added reductants at temperatures of ~200 °C. Studies were performed over BaNa-Y and related catalysts to unravel the roles that nitrates and nitrites play in determining the processes and pathways involved in NOx reduction. <o:p></o:p></span></p>...
Magnetic Resonance Imaging is a non-invasive modality that allows for deep-tissue imaging. Contrast agents decrease image acquisition time and increase the intrinsic contrast between different types of tissue. A new family of enzyme-activated contrast agents is emerging that has the ability to report on enzymatic processes in vivo. Towards this...
In this thesis we study minimal measures for Lagrangian systems on compact manifolds. This thesis consists of three parts which are closely related.
The first part is Chapter 3 and Chapter 4. In Chapter 3 and 4, we consider geodesic flows on compact surfaces with higher genus. We show that...
Although cementitious construction materials are mainly used in a large scale and in huge quantities, fundamental properties such as strength, ductility, creep, shrinkage, and fracture behavior depend, to a great extent, on structural elements and phenomena which are effective at the micro- and nanoscale. This research involves characterization of the...