Northwestern University

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Filtering by: Creator Kathleen Gifford Bickel Resource type Dissertation

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Src Family Kinase Phosphorylation of the Motor Domain of the Human Kinesin-5, Eg5

Description:

Spindle formation in mammalian cells requires precise spatial and temporal regulation of the kinesin-5 motor proteins which generate outward force to establish spindle bipolarity. A growing body of work suggests that phosphorylation of kinesin-5 motor domains is an important regulator of their motor characteristics and function in cells. My thesis...

Keyword:

mitosis,, kinesin-5, cytoskeleton, phosphorylation, Src family kinases, and drug resistance

Subject:

Driskill Graduate Training Program in Life Sciences

Creator:

Kathleen Gifford Bickel

Owner:

Scholarly Digital Publishing

Date Uploaded:

10/12/2018

Date Modified:

10/12/2018

Date Created:

2017-01-01

Resource Type:

Dissertation