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Description:: Histone methylation plays an important role as an epigenetic regulator, capable of driving stable, persistent changes in gene expression without changing a cell's genetic code. Previous work has used stable isotope labeling (SILAC) in combination with mass spectrometry to observe the relationship between the methylation of two neighboring lysine sites...
Keyword:: mass spectrometry, histone methylation, epigenetics, weighted least squares, and Markov
Subject:: Applied mathematics
Creator:: Yungster, Nir
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/01/2021
Date Created:: 2020-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_780806 and http://dissertations.umi.com/northwestern:15401

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