A number of nonclassical MHC Ib molecules recognizing distinct microbial antigens have been implicated in the immune response to Mycobacterium tuberculosis (Mtb). Due to the low polymorphism of MHC Ib molecules within the human population, these molecules and Mtb antigens are attractive targets for better vaccine development. Among these, HLA-E...
Early Modern Matters of Life and Death” argues that the political ecology of living, dead, and (in)animate beings in early modernity elucidates the claims of humanism and human exceptionalism that evolved in the period and that still inform present-day anthropogenesis
Graphene offers promising opportunities for applications in printed and flexible electronic devices due to its high electrical and thermal conductivity, mechanical flexibility and strength, and chemical and environmental stability. However, scalable production and processing of graphene presents a critical technological challenge preventing the application of graphene for flexible electronic interconnects,...
This dissertation studies fictionalized diasporic subalternity, how it is represented by the authors (of the same social status or a cosmopolitan writer), and how different types of agency layered onto the characters influence each other. The choice of texts includes Amitav Ghosh’s River of Smoke (2011), Kiran Desai’s Inheritance of...
AIMS: This study investigated the longitudinal effects of internal and external housing quality problems on child mental health outcomes, as measured by child internalizing and externalizing behavior problems. The study also aimed to elucidate the mechanisms through which housing quality problems affect child mental health by testing the mediating effects...
Education researchers have recently highlighted income achievement and behavior gaps – differences between children from high versus low income families in achievement scores and teacher-rated behavior. To date, scholars in this research stream have not considered the possibility that, compared to white students, non-white students may receive differential returns to...
Organizations comprise of groups who share and compete for resources. During organizational change, resources are often redistributed. Although change messages highlight overarching benefits for the organization, recipients of the message are interested in knowing how they will be affected at the group level, and this affects the way the message...
I use the current accounting rules for earnouts and the previous changes in the accounting rules for earnouts to examine three research questions. My first research question is whether accounting regulation has real effects on the use of earnouts. My second research question is whether the earnout liability represents the...
Metabolic abnormalities of cancers provide opportunities for novel tumor-specific therapies. Isocitrate dehydrogenases (IDHs) catalyze the oxidative decarboxylation of isocitrate to α-ketoglutarate (αKG) and the reduction of NAD(P)+ to NAD(P)H. Oncogenic mutations in two IDH-encoding genes (IDH1 and IDH2) have been identified in acute myelogenous leukemia, low-grade glioma, and secondary glioblastoma...