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Filtering by: Keyword Frontotemporal Dementia Resource type Dissertation

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Lysosomal Dysfunction due to PGRN Mutations in Frontotemporal Dementia

Description:

Frontotemporal dementia (FTD) encompasses a group of neurodegenerative disorders characterized by cognitive and behavioral impairments. Heterozygous mutations in progranulin (PGRN) cause familial FTD and result in decreased PGRN expression, while homozygous mutations result in complete loss of PGRN expression and lead to the neurodegenerative lysosomal storage disorder neuronal ceroid lipofuscinosis...

Keyword:

Progranulin, Frontotemporal Dementia, Lysosome, and Cathepsin D

Subject:

Neurosciences

Creator:

Valdez, Clarissa

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2017-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:14449 and etdadmin_upload_626172
Memory and Lexical Processing in Primary Progressive Aphasia

Description:

Primary Progressive Aphasia (PPA) is an aphasic dementia syndrome caused by neurodegenerative disease in which linguistic abilities are selectively disrupted in the relative absence of other cognitive deficits in early stages. The studies presented in this thesis were designed to examine the integrity of word and object processing by contrasting...

Keyword:

Dementia, Pictures, Recognition Memory, Frontotemporal Dementia, Words, and Priming

Subject:

Neuroscience Institute Graduate Program

Creator:

Emily Joy Rogalski

Owner:

Scholarly Digital Publishing

Date Uploaded:

05/28/2018

Date Modified:

05/28/2018

Date Created:

2007-04-27

Resource Type:

Dissertation

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Lysosomal Dysfunction due to PGRN Mutations in Frontotemporal Dementia

Memory and Lexical Processing in Primary Progressive Aphasia

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