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Filtering by: Keyword Gene expression Resource type Dissertation

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Statistical methods for the network-based analysis of genomic data

Description:

The focus of this thesis is on evaluating, designing, and applying statistical methods that elucidate molecular mechanisms by seeking to understand the pathways that contribute to disease. Chapter 1 introduces the field and motivates the work in this thesis. Chapters 2, 3, and 4 describe original work. Chapter 5 recapitulates...

Keyword:

Gene expression, Algorithms, Pathways, Networks, and Systems biology

Subject:

Statistics and Bioinformatics

Creator:

Shah, Sahil D

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:14812 and etdadmin_upload_685626
Sequence Determinants of Translation Efficiency

Description:

Bacterial gene expression requires numerous steps that are energetically costly and tightly regulated. Following transcription of messenger-RNA, the translation of mRNA into protein is further regulated by a variety of sequence features both within and upstream of coding sequences. Collectively, these features contribute to the control of translation initiation, elongation,...

Keyword:

Translation efficiency, Gene expression, Codon Usage Bias, and Shine-Dalgarno

Subject:

Interdepartmental Biological Sciences (IBiS) Graduate Program

Creator:

Adam John Hockenberry

Owner:

Scholarly Digital Publishing

Date Uploaded:

04/09/2018

Date Modified:

04/09/2018

Date Created:

2017-01-01

Resource Type:

Dissertation

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Statistical methods for the network-based analysis of genomic data

Sequence Determinants of Translation Efficiency

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