For stochastic simulation optimization in a modern computing era, we introduce a new parallel framework for solving very large-scale problems using a ranking & selection (R&S) approach that simulates all systems or feasible solutions to provide a global statistical guarantee. We propose a parallel adaptive survivor selection (PASS) framework that...
This dissertation formulates, solves and estimates dynamic stochastic games to answer various questions that arise in Industrial Organization. First chapter is a "theoretic" investigation of learning-by-doing and organizational forgetting that shows them to be distinct economic forces whose interplay gives rise to aggressive pricing behavior, market dominance, and multiple equilibria....
Actin polymerization is responsible for the protrusion of filopodia and lamellipodia in immune, cancer, and other motile cells, as well as for propulsion of some intra cellular pathogens. Protrusion of a lamellipodium by the very filaments supporting the membrane load operates by the Brownian ratchet mechanism, with overall organization governed...