This study is a response to the observation that people articulate meanings of rules in flexible and context-specific ways, but that literature on international legal, norm-based, strategic-logical, and ethical/moral rules typically treats them as pregiven, stable objects. By examining people’s evolving justifications of practices related to firefighting (protecting against and...
Over the last several decades, market-driven needs created a vast assortment of products with micron-sized features. To achieve the necessary levels of precision and accuracy, a synergistic approach was undertaken, where both material addition and subtraction was employed in the creation of the desired parts. However, currently employed micromanufacturing processes...
This dissertation is a wide-range study of the relationships between the three central elements of the production function: technology, capital and its financing, and labor. Chapter 1 analyzes the relationship between labor and recent wave of automation and digitization technologies, showing that while they typically substitute for workers, in several...
There has been significant growth in applying composite materials for various engineering applications in the past several decades. Composites allow engineers to tailor material microstructures and constituents for desired structural properties that usually outperform traditional engineering materials such as alloys. However, due to the heterogeneous nature of composites' microstructure, composite...
Uterine leiomyoma (LM), the most common tumor of women, causes severe morbidity. LM cells can be separated into three molecularly and functionally distinct cell populations based on the expression pattern of CD34 and CD49b: stem (LSC, CD34+/CD49b+), intermediate (LIC, CD34+/CD49b-), and differentiated cells (LDC, CD34-/CD49b-). Progesterone via progesterone receptor (PR/PGR)...
This thesis explores questions in labor economics and applied microeconomics, with particular focus on issues that have implications for public policy. The first essay estimates the Frisch elasticity, sometimes known as the wage elasticity of labor supply in response to anticipated wage changes. Despite its importance in macroeconomic and public...
Over 6 million adults in the United States have heart failure, a serious public health problem. Differences in the progression of heart failure are in part due to variability in sex, age, and genetic variation background including ancestry. Medical biobanks provide a resource to study this variability as they include...
This dissertation presents research on the game theory of political power, both between and within nations. It first revisits a classical distinction between three different types of power or influence: information, rewards and threats. By presenting a binary-action Principal-Agent problem which incorporates the essential ingredients of all three types of...
The advent of sequencing technologies has generated a large amount of biological and medical data. These data such as genetic sequencing data and lab experimental evidence data can help understand critical biomedical problems. This dissertation makes contribution in three different but related applications in biomedical research. In Chapter 2, we...
Natural products from fungi have had an immeasurable societal impact as both friends and foes to human health. This includes numerous therapeutics that have had widespread clinical success, mycotoxins that are implicated in fungal pathogenicity, and various agrochemicals. Recent genome sequencing efforts have revealed that fungal genomes contain the capacity...