Northwestern University

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Filtering by: Creator Graham R Lawton Resource type Dissertation

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Part 1: Synthesis of Side-Chain Functionalized Polyamines and Study of their RNA-Binding Properties. Part 2: Synthesis and Evaluation of Heterocycle-Based Selective Inhibitors of Neuronal Nitric Oxide Synthase with Improved Bioavailability.

Description:

Part 1. The complex folded structures associated with RNA allow for specific protein-RNA interactions and also create binding sites for small molecules. Developing organic molecules that can bind RNA with high affinity and specificity is a challenge that must be overcome for RNA to be considered a viable drug target....

Keyword:

Chemistry

Subject:

Chemistry

Creator:

Graham R Lawton

Owner:

Scholarly Digital Publishing

Date Uploaded:

06/26/2018

Date Modified:

06/26/2018

Date Created:

2007-05-03

Resource Type:

Dissertation