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- Description:
- Dopamine (DA) neurons are involved in many brain functions, and their dysfunction is associated with several neurodegenerative diseases. In recent years, our lab and others have found that DA neurons are molecularly diverse through single-cell gene expression profiling. An outstanding question in the field is whether this heterogeneity is encoded...
- Subject:
- Developmental biology
- Creator:
- Pereira Luppi, Maria Milagros
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16348 and etdadmin_upload_945123
-
- Description:
- Selecting the best material to deliver optimum performance in real-world applications is one of the most significant challenges in engineering. Hundreds of thousands of computationally-predicted, but experimentally unexplored materials exist today in the public inorganic material databases as candidates for consideration. This thesis discusses three projects in the domain of...
- Keyword:
- statistical modeling, materials design, uncertainty quantification, materials selection, computational materials, and materials informatics
- Subject:
- Materials Science
- Creator:
- Gopakumar, Abhijith Mini
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_947056 and http://dissertations.umi.com/northwestern:16368
-
- Description:
- This research questions how institutional logics shape and change through the event sequencing of institutional reforms. Literature reviewed on sequences of social events underspecifies the enchainment of events, i.e., the set of social processes that both links events and also renders the sequence meaningful beyond summing its individual events. My...
- Keyword:
- institutional logics, institutional reforms, organizational institutionalism, Latin America, event sequencing, and qualitative methods
- Subject:
- Management and Organization theory
- Creator:
- Milner, Daniel
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_941589 and http://dissertations.umi.com/northwestern:16331
-
- Description:
- Superconducting-circuit based platforms are strong contenders in the race to build a quantum computer.While the transmon has had extraordinary success as the leading superconducting qubit modality, there are reasons to believe that other types of qubits could possess relative benefits in terms of noise immunity, anharmonicity, or extensibility. In this...
- Keyword:
- fluxonium, Superconducting circuits, Quantum computing, and current mirror
- Subject:
- Physics and Quantum physics
- Creator:
- Weiss, Daniel Kamrath
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_933500 and http://dissertations.umi.com/northwestern:16292
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- Description:
- Fat represents an important source of energy for ovarian cancer (OC) cells and is supplied either through import from the tumor milieu or via de novo lipogenesis. During fast tumor growth, when nutrients are scarce, lipogenesis becomes the primary source of fatty acids. Stearoyl-CoA desaturase (SCD), a rate-limiting enzyme in...
- Keyword:
- ER stress, Fatty acids, Ovarian cancer, and Lipid metabolism
- Subject:
- Bioinformatics, Oncology, and Cellular biology
- Creator:
- Zhao, Guangyuan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_940639 and http://dissertations.umi.com/northwestern:16324
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- Description:
- From the early usage of metallic thin films as mirrors tracing back to 2900 BC, to the modern thin film photonic circuits as a mature optical processing platform, and to the growing class of atomically-thin two-dimensional (2D) materials with diverse and tailorable properties, thin film materials have played an important...
- Keyword:
- Two-dimensional materials, Photonic circuits, Thin film materials, Topological photonics, Electron-beam lithography, and Optical materials
- Subject:
- Physics and Materials Science
- Creator:
- Liu, Pufan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_946295 and http://dissertations.umi.com/northwestern:16358
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- Description:
- Since the dawn of mankind, humans have used materials and tools to dominate the world. As our understanding of the fields physics, chemistry and engineering is growing, we are able to artificially create advanced materials with engineered responses. Next step would be to create ‘ smart’ or intelligent materials capable...
- Keyword:
- Hydrogels, Soft Active Materials, Continuum modeling, Finite element, and Soft matter
- Subject:
- Physics
- Creator:
- Aggarwal, Aaveg
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_932341 and http://dissertations.umi.com/northwestern:16286
-
- Description:
- Public-facing data-driven technologies such as social media platforms and search engines rely on data producers, such as users and crowd workers, to be feasible and financially sustainable. Recently, it became clear that the goals of these data-driven technologies do not always align with those of the public, causing public backlashes...
- Subject:
- Computer science and Communication
- Creator:
- Li, Hanlin
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16375 and etdadmin_upload_947289
-
- Description:
- Deterministic models are used to explain and predict the dynamics of ecosystems featuring cyclic competition schemes. The models are systems of reaction-diffusion partialdifferential equations that account for species mobility via Fickian diffusion and interspecies interactions according to the competition scheme. Length and temporal scales are chosen to be appropriate for...
- Keyword:
- cyclic ecosystems, nonlinear dynamics, rock-paper-scissors, traveling waves, exceptional species, and computational ecology
- Subject:
- Ecology and Applied mathematics
- Creator:
- Stiadle, Thomas Isaac
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_946682 and http://dissertations.umi.com/northwestern:16361
-
- Description:
- From colonial practices designed to civilize indigenous communities, to counter-terrorism initiatives aimed at de-radicalizing dissidents in the wake of the War on Terror, to controversies over blasphemy and religious harm cases in international law, religious passions have been cast as a specter of unreason, treason, and radicalization. These assumptions sustain...
- Keyword:
- Emotion, Religion, International Law, Affect, Human Rights, and Political Theory
- Subject:
- Religion, International relations, and Political science
- Creator:
- Giliberti, Gina Camille
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16359 and etdadmin_upload_946425