Northwestern University

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Filtering by: Subject Neurosciences Subject Virology

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The Role of the Host Response and Viral Genetic Variation in the Pathogenesis of Herpes Simplex Encephalitis

Description:

Herpes simplex virus (HSV) encephalitis (HSE) is the most common cause of sporadic fatal encephalitis, and despite targeted antiviral therapy, outcomes remain poor. While rare in adults, neonates are significantly more susceptible to severe HSV disease. Understanding both the host and viral factors that contribute to pathogenesis is critical to...

Keyword:

Inflammasome, Neonate, Encephalitis, and Herpes

Subject:

Virology, Immunology, and Neurosciences

Creator:

Hayes, Cooper Kincaid

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

06/22/2022

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_903123 and http://dissertations.umi.com/northwestern:16088