Limit your search
- Neurosciences[remove]134
- Molecular biology12
- Biomedical engineering11
- Biology10
- Cognitive psychology9
- more Subjects »
Search Constraints
Number of results to display per page
Search Results
-
- Description:
- Our sense of smell, or olfaction, is one of our most evolutionarily ancient senses. In vertebrates, olfaction plays a crucial role in many functions, such as detecting and evaluating food, avoiding predators, regulating appetite, spatial navigation, and selecting mating partners. In addition, the olfactory system is highly dynamic and exhibits...
- Keyword:
- Neuroimaging, Perceptual Coding, Olfaction, Encoding Models, and Orbitofrontal Cortex
- Subject:
- Neurosciences
- Creator:
- Sagar, Vivek
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16580 and etdadmin_upload_986169
-
- Description:
- Findings in both humans and animal models have associated the hippocampal theta oscillation with hippocampal memory function. In animal models, previous research supports that the theta oscillation contributes to memory via phase-dependent changes in hippocampal network connectivity, wherein memory encoding versus retrieval are optimized at different phases of the theta...
- Keyword:
- theta, intracranial, phase, TMS, oscillation, and hippocampus
- Subject:
- Neurosciences
- Creator:
- Lurie, Sarah M
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_956997 and http://dissertations.umi.com/northwestern:16394
-
- Description:
- Aging is the greatest known risk factor for Alzheimer’s Disease (AD); however, the molecular mechanisms underlying aging and how it can initiate and or exacerbate AD, is still unknown. Epigenetic regulation has been widely accepted to play an essential role in aging or AD-related processes; however, whether dysregulations of histone...
- Keyword:
- HDACs, Alzheimer's Disease, Epigenetics, and Aging
- Subject:
- Neurosciences
- Creator:
- McClarty, Bryan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_954939 and http://dissertations.umi.com/northwestern:16390
-
- Description:
- Simple sensorimotor tasks, such as lifting a cup or balancing a tray, requires not only controlled motor output, but also the ability to accurately perceive sensory information. After a hemiparetic stroke, individuals often experience sensory deficits in addition to motor impairments. However, research on the extent of changes in sensory...
- Subject:
- Physical therapy, Robotics, and Neurosciences
- Creator:
- Cai, Ninghe May
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 03/24/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16418 and etdadmin_upload_962539
-
- Description:
- Voltage-gated potassium (KV) currents play a crucial role in shaping and controlling the firing patterns that serve as the fundamental basis for the differential signal processing from the ear to the auditory cortex, with distinct firing patterns observed with high- and low-frequency phenotypes. This is an interesting phenomenon, in the...
- Keyword:
- Ising model, auditory system, Tonotopy, action potential, cochlear nucleus, and Potassium channel
- Subject:
- Biophysics and Neurosciences
- Creator:
- Takahashi, Momoko
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 03/24/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16410 and etdadmin_upload_962033
-
- Description:
- Aging is the greatest known risk factor for Alzheimer’s Disease (AD); however, the molecular mechanisms underlying aging and how it can initiate and or exacerbate AD, is still unknown. Epigenetic regulation has been widely accepted to play an essential role in aging or AD-related processes; however, whether dysregulations of histone...
- Keyword:
- HDACs, Alzheimer's Disease, Epigenetics, and Aging
- Subject:
- Neurosciences
- Creator:
- McClarty, Bryan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 03/24/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_954939 and http://dissertations.umi.com/northwestern:16390
-
- Description:
- The retina detects light, processes the visual signal, and sends a complex set of parallel information channels to the brain via a functionally diverse set of retinal ganglion cells types. This manuscript examines these retinal ganglion cell types, the visual features they encode, and the computational mechanisms leading to their...
- Keyword:
- electrophysiology, computational, signal processing, Bipolar cell, Retina, and ganglion cell
- Subject:
- Ophthalmology and Neurosciences
- Creator:
- Swygart, David Isaiah
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 03/24/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_962145 and http://dissertations.umi.com/northwestern:16411
-
- Description:
- Human olfactory function is important for a myriad of behaviors, including food seeking, social cognition, memory, emotional regulation, and detecting environmental threats. In animal models, particularly dense olfactory inputs have been shown to target orbitofrontal cortex (OFC), a region involved in multimodal sensory integration, reward coding, and flexibly guiding our...
- Keyword:
- aging, tractography, olfaction, alzheimer's disease, orbitofrontal cortex, and diffusion magnetic resonance imaging
- Subject:
- Neurosciences
- Creator:
- Echevarria-Cooper, Shiloh Luela
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 03/24/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16387 and etdadmin_upload_952134
-
- Description:
- Findings in both humans and animal models have associated the hippocampal theta oscillation with hippocampal memory function. In animal models, previous research supports that the theta oscillation contributes to memory via phase-dependent changes in hippocampal network connectivity, wherein memory encoding versus retrieval are optimized at different phases of the theta...
- Keyword:
- oscillation, hippocampus, phase, TMS, theta, and intracranial
- Subject:
- Neurosciences
- Creator:
- Lurie, Sarah M
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 03/24/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_956997 and http://dissertations.umi.com/northwestern:16394
-
- Description:
- Dopamine neurons are characterized by their response to unexpected rewards, but some also fire during movement and in response to aversive stimuli. Dopamine neuron diversity has also been observed based on their genetic expression profiles, suggesting that different functions might map onto such genetic subtypes. However, this has not been...
- Keyword:
- Subtypes, Striatum, Dopamine, and SNc
- Subject:
- Neurosciences
- Creator:
- Azcorra, Maite
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16371 and etdadmin_upload_947134
-
- Description:
- Electrical spinal cord stimulation is an emerging treatment for spinal cord injury that can improve walking and bladder control, among many other functions. While the anatomical location of the motor pools for muscles involved in locomotion in the lumbosacral cord has been identified, the map of the functional output of...
- Subject:
- Neurosciences
- Creator:
- Patterson, Jacqueline
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16163 and etdadmin_upload_917878
-
- Description:
- The current view in neuroscience holds that the brain, together with its sensory and motor structures and the environment, form a closed-loop system – a sensorimotor loop – in which the brain receives information from the environment and converts it into a motor response while simultaneously making predictions about future...
- Subject:
- Biomedical engineering, Computer science, and Neurosciences
- Creator:
- Zweifel, Nadina Olivia
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16198 and etdadmin_upload_925059
-
- Description:
- Affect represents a major domain of human consciousness, consisting of a complex group of psychophysiological processes to drive human behavior. Many genetic and environmental factors may cause dysregulation of affective states, resulting in disorders that severely disrupt normal cognitive function and diminish the quality of life. Transitions among affective states...
- Keyword:
- Dopamine, Optogenetics, and Affective disorders
- Subject:
- Neurosciences
- Creator:
- Wu, Mingzheng
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_925290 and http://dissertations.umi.com/northwestern:16201
-
- Description:
- Cholinergic modulation of the brain cortex is critical for cognitive processes, and altered cholinergic modulation of the prefrontal cortex is emerging as an important mechanism of neuropathic pain. Despite the known sex differences in pain prevalence and perception, the precise nature of the mechanisms responsible for sexual dimorphism in chronic...
- Keyword:
- acetylcholine, cholinergic modulation, prefrontal cortex, and pain
- Subject:
- Neurosciences
- Creator:
- Jefferson, Taylor
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16249 and etdadmin_upload_928522
-
- Description:
- Persons with spinal cord injuries can use state-of-the-art brain-computer interfaces to control robotic arms. Despite this high-tech solution, their movements are slow and imprecise, much like those made by individuals who have lost proprioception, the sense of body position and movement. Intracortical microstimulation (ICMS) used to reactivate neural circuits in...
- Keyword:
- proprioception, stimulation, prosthetic, and sensory
- Subject:
- Biomedical engineering and Neurosciences
- Creator:
- Sombeck, Joseph T
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_917097 and http://dissertations.umi.com/northwestern:16157
-
- Description:
- The answer to the question “Why do we sleep?” lies in understanding the biological underpinnings of homeostatic drive to sleep. Wakefulness is correlated with numerous changes in brain activity, structure and gene/protein expression that re-normalize following sleep however which of these elements is sufficient to cause sleep drive and how...
- Keyword:
- Circadian, Homeostasis, Sleep, Drosophila, and Time
- Subject:
- Neurosciences
- Creator:
- Andreani-fabroni, Tomas Sergio
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_906530 and http://dissertations.umi.com/northwestern:16115
-
- Description:
- Research over the past several decades has revealed that memory reactivation in sleep contributes to the formation of long-lasting memories. Among the most recent developments in this field is the widespread use of the technique of targeted memory reactivation (TMR), which allows researchers to induce reactivation of specific memories during...
- Keyword:
- sleep, sleep disruption, memory replay, memory consolidation, targeted memory reactivation, and wearables
- Subject:
- Cognitive psychology and Neurosciences
- Creator:
- Whitmore, Nathan Winter
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_915410 and http://dissertations.umi.com/northwestern:16141
-
- Description:
- Over the course of disease progression, half of adults with type II diabetes also develop diabetic peripheral neuropathy (DPN), peripheral nerve damage precipitated by the downstream metabolic effects of hyperglycemia, insulin resistance, and dyslipidemia. This multifactorial pathogenesis of DPN leads to various structural and physiological changes within the nerve, ultimately...
- Keyword:
- Diabetic neuropathy, Diagnostic medicine, Peripheral nerve, Mechanical properties, Shear wave elastography, and Ultrasound
- Subject:
- Neurosciences
- Creator:
- Rugel, Chelsea Lynne
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_927674 and http://dissertations.umi.com/northwestern:16229
-
- Description:
- Perturbations to the physiology or impairments in the formation of synapses within the cochlea, specifically the ribbon synapses, result in decreased sensitivity to auditory stimuli. In example, prolonged exposure to moderately intense auditory stimuli, like power tools, can result in the swelling of nerve terminals, retraction of the postsynaptic membrane,...
- Keyword:
- Hearing, Neuroligins, Proteomics, Ribbon Synapse, ASD, and NIHL
- Subject:
- Neurosciences
- Creator:
- Ramirez, Miguel Angel
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16120 and etdadmin_upload_909763
-
- Description:
- In the adult hippocampus of many mammalian species, populations of newborn dentate granule cells (DGCs) are continuously generated and undergo subsequent activity-dependent neuronal maturation and incorporation into the preexisting hippocampal circuitry. Increasing evidence has demonstrated that these young adult-born DGCs (abDGCs) participate in numerous cognitive and affective processes such as...
- Keyword:
- Neurogenesis, GABA, Adult-born granule cell, Kainate receptor, and GluK2
- Subject:
- Neurosciences
- Creator:
- Zhu, Yiwen
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15903 and etdadmin_upload_874789